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Experts are sounding the alarm over a new side effect linked to popular weight-loss injections like Ozempic, Wegovy, and Mounjaro, coining the term "Ozempic hands." This phenomenon describes a dramatic thinning of the hands and fingers, leaving them appearing skeletal as patients experience rapid fat and muscle loss. The issue was first noted when the drugs gained popularity, with some users requiring resized rings due to their slimmer fingers. Social media has reignited interest in this side effect, particularly after viral videos compared the hands of celebrities like Khloe Kardashian, whose fingers appear noticeably thinner now than a decade ago. While Kardashian has not confirmed using these injections, she has previously expressed willingness to try them during her weight-loss journey. Pharmacist Deborah Grayson explains that "Ozempic hands" are a visual consequence of rapid weight loss rather than a direct side effect of the medication. Although not harmful, this change can be permanent unless patients regain weight. Cosmetic treatments to restore volume are available but can be costly. Other celebrities, including Oprah Winfrey and Sharon Osbourne, have also displayed signs of this side effect, with Osbourne even suffering from what’s referred to as "Ozempic feet." The trend of aesthetic changes linked to these drugs extends beyond hands, with terms like "Ozempic face" and "Ozempic butt" emerging as users report sagging skin due to rapid fat loss. As these weight-loss jabs become more accessible—now being prescribed by GPs rather than exclusively at specialist clinics—experts warn that the aesthetic fallout, including excess skin issues, may lead to increased demand for cosmetic surgery. With around 350,000 patients expected to receive these medications through the NHS in 2024, the implications of these treatments are likely to grow, prompting the need for ongoing discussions about their risks and benefits.

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