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Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: The UNEXPECTED Ozempic Weight Loss Body Scan Results (DEXA): https://www.youtube.com/watch?v=C_Z7qPVRA5M Check out the BBC article about GLP-1 agonists and aging: https://www.bbc.com/news/articles/ce81j919gdjo Check out the CNN article about GLP-1 agonists and cardiovascular disease risk: https://edition.cnn.com/2024/09/18/health/glp-1-prevent-heart-attack-stroke/index.html Recent articles from outlets such as the BBC and CNN reported that GLP-1 agonists such as Ozempic, a drug used for the treatment of type 2 diabetes and obesity, may help lower risk and death rates from several diseases including COVID-19 and heart failure. Matt and Nick discuss mechanisms by which GLP-1 agonists might slow the biological aging process, the connection between health and biological age, and the potential for future, more effective versions of these drugs. They also touch on the importance of diet quality, protein intake, resistance training, and regular bloodwork and hormone profiling to understand the effects of GLP-1 agonists on the body and to mitigate potential side effects such as muscle and bone loss. GLP-1 agonists are medications that mimic the action of a hormone called glucagon-like peptide-1 (GLP-1), which is naturally produced in the gut, to manage type 2 diabetes. They regulate blood sugar levels by stimulating insulin release when blood sugar levels are high, slowing down digestion, and reducing the liver’s production of glucose. In recent years, GLP-1 agonists have gained attention for their role in weight management. By affecting appetite control centers in the brain, they help people feel fuller for longer, leading to reduced food intake and weight loss. 0:00 Introduction 1:15 Why are GLP-1 agonists receiving attention for life extension right now? 2:46 Do GLP-1 agonists affect the biology of aging? 5:28 Does anything that improves health also slow aging by default? 13:00 Are there more GLP-1 agonists in the pipeline? 23:03 Do we need more studies to determine who should take GLP-1 agonists? 26:09 An elevator pitch as to why someone should take a GLP-1 agonist Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://twitter.com/optispanpodcast Twitter: https://twitter.com/optispan Twitter: https://twitter.com/mkaeberlein Linkedin: https://www.linkedin.com/company/optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!

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New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/ DESCRIPTION: Harvard study found that men and women eating low carb diets live significantly shorter lives, but what about the "eco-Atkins diet," a plant-based low carbohydrate diet? Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/videos/plant-based-atkins-diet/ and I'll try to answer it! Image Credit: Stacy Spensley / Flickr https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books: https://nutritionfacts.org/books • Shop: https://drgreger.org

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If you have a double chin, I think the first thing you should do is get on the Healthy low carb diet and practice intermittent fasting. START HERE: https://youtu.be/XjTBV4LqWuw This should help you get rid of the excess fat. If someone has a round face, they have too much insulin and consume too many carbs. I was also storing a lot of water because, with every gram of glucose stored as glycogen, three grams of water are stored. In addition to that, you may want to try these exercises for a double chin. If you’re looking for detailed guidance and personalised nutrition and training, DM me “coaching” on Instagram or email me on [email protected] Thumbnail designed by @rachitxdesign on Instagram. #facefat #transformation #jawline

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Today, I want to talk about plastic surgery after weight loss through GLP-1 medications like Ozempic. For the past 20 years, I’ve been helping patients who’ve lost significant weight, whether through gastric bypass or other surgeries, and in recent years, we’ve seen a rise in patients losing weight with GLP-1 medications. While the weight loss process is similar, I've noticed that patients on Ozempic tend to lose more skeletal muscle compared to those who underwent traditional weight loss surgery. This results in issues like "Ozempic face," which requires facial rejuvenation, and skin laxity or "Ozempic body" in areas like the arms, abdomen, and thighs, often needing a lift. For those with buttock deflation, both fatty tissue and skeletal muscle loss, buttock augmentation and reshaping are necessary. Overall, the outcomes from weight loss surgeries and Ozempic are quite similar, but in some cases, additional skeletal mass augmentation, like in the buttocks, is needed for optimal results. #drsiamakagha #newportbeachplasticsurgery #thighreduction #lowerbodylift #skinlaxity #looseskin #skinremovalsurgery #bodyliftsurgery #wls #weightlosssurgery #weightloss #ozempic #mounjaro #boardcertifiedplasticsurgeon #semaglutide #Bariatric #vsg #glp1 #glp1weightloss #glp1community

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Zepbound and Wegovy are both GLP-1 receptor agonists used for weight loss, but they differ in their active ingredients and how they work. Wegovy contains semaglutide, while Zepbound uses tirzepatide, which targets both GLP-1 and GIP receptors—potentially offering greater weight loss effects. Clinical studies have shown that Zepbound may lead to more significant weight loss results compared to Wegovy, making it a strong contender for those struggling with obesity. However, individual responses vary, and side effects like nausea or gastrointestinal discomfort are common with both. The choice between them often comes down to personal tolerance, cost, and physician guidance.

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🔥 3-Minute Fat-Burning & Muscle-Building Workout! 💪 Short on time but still want results? This 3-minute full-body workout is designed to burn fat, build muscle, and boost your energy — no equipment needed! Whether you're at home, in the office, or on the go, this quick routine will push your limits and help you stay fit! ✅ What to expect: ✔️ High-intensity movements ✔️ Full-body activation ✔️ Fat-burning cardio ✔️ Muscle-toning exercises 🕒 Only 3 minutes — that’s all you need to get started on your fitness goals. Repeat for multiple rounds if you're up for the challenge! 💬 Drop a comment to let us know how many rounds you completed! 🔔 Don’t forget to like, subscribe, and hit the notification bell for more quick & effective workouts! #FatBurningWorkout #BuildMuscle #HomeWorkout #QuickWorkout #3MinuteWorkout #BodyweightWorkout #NoExcuses #FitnessMotivation