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I started close to 300 lbs. Lost 50 pounds naturally with diet and exercise, then hit a wall. PCOS made losing weight feel impossible. My hormones were out of whack, and my body refused to budge no matter how disciplined I was. That’s when I decided to try GLP-1 medication and it changed everything. Another 20 pounds gone. Energy is back. Cravings down. Confidence up. 💖 If you’re dealing with PCOS or feel like your body’s working against you, you’re not alone. 👇 Curious what helped me break the plateau? Here’s the program I recommend: Get $50 off your first purchase when you sign up using code SOULVIA 👉 https://www.ldfbem4trk.com/C9JN8J/2CTPL/?source_id=YouTube (Affiliate link. I may earn from qualifying sign-ups — thank you for your support!)

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El avance de Eli Lilly: una revolución needle-free en diabetes y obesidad • Eli Lilly ha dado un paso histórico con su nueva pastilla oral, orforglipron, que logró resultados positivos en su primer ensayo clínico de fase avanzada con pacientes de diabetes tipo 2. • Este avance representa una alternativa más accesible y cómoda frente a las inyecciones, abriendo la puerta a una mayor adherencia y alcance, especialmente en comunidades con barreras de acceso a la salud como la latina

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Calling all those with a passion for cardiovascular prevention! In this episode of the CardioNerds Cardiovascular Prevention Series, we take a deep dive into the world of glucagon-like peptide-1 (GLP-1) receptor agonists. Along the way, you’ll hear about the biology of the GLP-1 molecule and its related peptides, learn more about how GLP-1 agonists promote glycemic control, weight loss, and cardiometabolic health, and explore the current body of literature supporting the individualized application of these medications to patients with diabetes, obesity, and/or ASCVD. Join Dr. Christian Faaborg-Andersen (CardioNerds Academy Fellow and Internal Medicine Resident at MGH), Dr. Gurleen Kaur (Director of the CardioNerds Internship, Chief of House Einthoven, and Internal Medicine resident at BWH), and Dr. Rick Ferraro (CardioNerds Academy House Faculty and Cardiology Fellow at JHH) for a wide-ranging discussion on GLP-1 and GIP agonists with Dr. Dennis Bruemmer (Cardiologist and Director of the Center for Cardiometabolic Health in the section of Preventive Cardiology at the Cleveland Clinic). Show notes were drafted by Dr. Christian Faaborg-Andersen. Audio editing was performed by CardioNerds Academy Intern, student Dr. Tina Reddy. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - GLP-1 Agonists: Mechanisms to Applications The selection and dosing of GLP-1 and GIP agonists (GLP-1s and GIPs) depends on their intended use as an anti-glycemic or anti-obesity agent. The cardiovascular benefits of GLP-1s and GIPs may be independent of improvements in glycemic control, and in part be driven by reduction in inflammation, a key driver of arterial plaque formation. In patients with comorbid coronary artery disease, obesity, and diabetes, GLP-1 agonists and SGLT-2 inhibitors should be used as first-line agents, over metformin. Tirzepatide is a dual agonist that activates GIP and GLP-1 receptors. GIP is highly expressed in the brain, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Caution should be used with GLP-1 agonists in patients with long-standing diabetes complicated by gastroparesis, as well as incompletely treated diabetic retinopathy. GI upset is not uncommon with GLP-1/GIP agonists, and switching to a different agonist is unlikely to help.  Show notes - GLP-1 Agonists: Mechanisms to Applications What are the mechanisms of action by which GLP-1 and GIP controls blood sugar and body weight? Glucagon-like peptide-1 (GLP-1) is an endogenous hormone that is secreted in response to an oral glucose load. It promotes insulin release, inhibits glucagon secretion, and slows gastric emptying via the brain-intestine axis, leading to satiety. GLP-1 agonists are medications that mimic the effect of this hormone and, on average, lower hemoglobin A1C by 0.8% to 1.5%. These medications include semaglutide, liraglutide, and dulaglutide. Glucose-dependent insulinotropic polypeptide (GIP) is also an endogenous hormone, similarly secreted by the body in response to an oral glucose load such as a meal. GIP is highly expressed in the arcuate nucleus and hypothalamus, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Tirzepatide is a dual GLP-1/GIP agonist. What is the role of GLP-1/GIP agonists in patients with overweight/obesity and/or type 2 diabetes? How does the dosing of GLP-1/GIP medications change with their intended disease target?

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Menxi Keto Gummies fills in as an ally for those embracing the keto way of life. The keto diet includes decreasing starch admission while expanding the utilization of sound fats and proteins, inciting the body to enter a condition of ketosis, where it consumes fat for fuel rather than carbs.

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Are you stuck in a weight loss plateau and feeling frustrated? In this video, we'll explore the top reasons why you're not losing weight and provide you with actionable tips to break through the plateau and reach your weight loss goals. From identifying hormonal imbalances to tweaking your workout routine, we'll dive into the most effective strategies to get you back on track. Whether you're a beginner or a seasoned dieter, this video is perfect for anyone looking to overcome a weight loss plateau and achieve sustainable weight loss. So, let's get started and break through that plateau once and for all!

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Are you looking for an advanced keto support option to help you on your weight loss journey? Look no further than Keto Clean+ Gummies! These gummies are designed to provide your body with the support it needs to stay in ketosis and burn fat more efficiently. With their unique blend of ingredients, they are sure to help you reach your weight loss goals faster and easier than ever before.

Benefits of Keto Clean+ Gummies

1. Increased Fat Burn: The main goal of the keto diet is to put your body into a state of ketosis, where it burns fat for energy instead of carbs. Keto Clean+ Gummies help support this process, allowing you to burn more fat and lose weight faster.

2. Boosted Energy Levels: Many people experience a significant increase in energy levels when following a keto diet. Keto Clean+ Gummies can help you maintain this energy throughout the day, making it easier to stay active and achieve your fitness goals.

3. Appetite Control: One of the biggest challenges of any weight loss journey is controlling your appetite. Keto Clean+ Gummies contain ingredients that help curb cravings and keep you feeling full, making it easier to stick to your diet and avoid overeating.

How to Use Keto Clean+ Gummies

1. Take as Directed: To see the best results, it is important to follow the recommended dosage instructions for Keto Clean+ Gummies. Typically, this involves taking one to two gummies daily with a glass of water.

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2. Pair with a Keto Diet: While Keto Clean+ Gummies can be beneficial on their own, they work best when combined with a keto-friendly diet. Make sure to focus on eating low-carb, high-fat foods to maximize the effects of the gummies.

3. Stay Hydrated: Drinking plenty of water is essential for any weight loss journey, including when taking Keto Clean+ Gummies. Staying hydrated helps support your metabolism and overall health, ensuring you see the best results.

Potential Side Effects of Keto Clean+ Gummies

1. Digestive Issues: Some people may experience digestive issues such as bloating, gas, or diarrhea when first starting Keto Clean+ Gummies. These symptoms typically subside as your body adjusts to the ingredients.

2. Keto Flu: As your body transitions into ketosis, you may experience symptoms commonly referred to as the “keto flu,” including headaches, fatigue, and irritability. Keto Clean+ Gummies can help support your body through this phase.

3. Allergic Reactions: While rare, some individuals may be allergic to certain ingredients in Keto Clean+ Gummies. If you experience any allergic reactions such as itching, swelling, or difficulty breathing, discontinue use immediately and consult a healthcare professional.

Is Keto Clean+ Gummies Right for You?

Overall, Keto Clean+ Gummies can be a valuable tool in your weight loss journey, especially if you are following a keto diet. By providing your body with the support it needs to stay in ketosis, burn fat, and control your appetite, these gummies can help you reach your goals faster and more efficiently. However, it is important to consult with a healthcare provider before starting any new supplement regimen to ensure it is safe and effective for you.

Are you ready to take your weight loss journey to the next level with Keto Clean+ Gummies? Order yours today and experience the benefits for yourself!

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McDonald’s (MCD) stock has been on a roller coaster ride lately. While it recently rebounded to close near $292, it’s still down 8% over the past month and nearly flat year-to-date. In this video, we break down whether the golden arches remain a strong long-term investment or if recent challenges signal deeper trouble. We’ll cover McDonald’s dividend history, with an astounding 49 consecutive years of payout increases and a current yield of 2.43%. Learn how its franchise business model, owning over 93% franchised restaurants, helps maintain strong cash flow even in turbulent markets. We’ll also discuss risks, including the impact of GLP-1 weight-loss drugs like Ozempic on consumer behavior and McDonald’s earnings outlook. Despite short-term revenue pressures, the company generates over $6.3 billion in free cash flow and maintains a 45.5% operating margin. Analysts have a consensus “Hold” rating with an average price target of $321.79, implying potential upside. Whether you’re a dividend investor or considering adding MCD to your portfolio, this analysis will help you make informed decisions about McDonald’s stock. #McDonalds #MCD #DividendStocks #StockAnalysis #Investing #stocks #dividends #fastfood #passiveincome #wealthbuilding #mcdonaldsstock #mcdonaldsinvestment #mcdstock #dividendaristocrats #stockmarket