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Three drugs: Liraglutide (Saxenda), Semaglutide (Wegovy), and Tirzepatide (Zepbound / Mounjaro) have been licensed for weight loss in patients who are overweight or obese. In this video I will discuss the mechanisms of action of these medicines, the licensed indications, method of administration, efficacy, side effects, and what happens to body weight after stopping treatment. TIMESTAMPS: 00:00 Introduction 00:26 Licensed Drugs 01:37 Mechanisms of Action 05:45 Licensed Indications 06:32 Method of Administration 07:14 Efficacy 08:49 Side Effects 09:47 Stopping Treatment References: Liraglutide: . SCALE Diabetes trial: https://pubmed.ncbi.nlm.nih.gov/26284720/ . SCALE Maintenance trial: https://pubmed.ncbi.nlm.nih.gov/23812094/ . SCALE Obesity & Prediabetes: https://pubmed.ncbi.nlm.nih.gov/26132939/ Semaglutide: . STEP 1 trial: https://pubmed.ncbi.nlm.nih.gov/33567185/ . STEP 2 trial: https://pubmed.ncbi.nlm.nih.gov/33667417/ . STEP 3 trial: https://pubmed.ncbi.nlm.nih.gov/33625476/ . STEP 4 trial: https://pubmed.ncbi.nlm.nih.gov/33755728/ Tirzepatide: . SURMOUNT 1: https://pubmed.ncbi.nlm.nih.gov/35658024/ . SURMOUNT 2: https://pubmed.ncbi.nlm.nih.gov/37385275/ . SURMOUNT 3: https://pubmed.ncbi.nlm.nih.gov/37840095/ . SURMOUNT 4: https://pubmed.ncbi.nlm.nih.gov/38078870/ Liraglutide vs Semaglutide: . STEP 8 trial: https://pubmed.ncbi.nlm.nih.gov/35015037/ What happens to body weight after stopping treatment: . SURMOUNT 4: https://pubmed.ncbi.nlm.nih.gov/38078870/ . STEP 4 trial: https://pubmed.ncbi.nlm.nih.gov/33755728/ . Liver Inte. 2019;39:941-949: https://pubmed.ncbi.nlm.nih.gov/30721572/ Other References: Effect of dual GIP / GLP-1 on Weight loss: https://pubmed.ncbi.nlm.nih.gov/36909312/ This video is purely of educational purposes and is intended for primary care physicians. It is not and should not be used by patients to treat themselves. The advice is to always speak to your doctor and follow his or her advice with regards to any condition you have or any treatment you are likely to undertake. #semaglutide #tirzepatide #wegovyweightloss #mounjaroweightloss #weightlossmedication #saxenda #glp1
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The keto diet has taken the world by storm in recent years, with many people experiencing incredible weight loss and health benefits by following this high-fat, low-carb eating plan. As the keto trend continues to grow, new products and supplements are constantly being introduced to help people achieve their weight loss goals. One such product that has caught the attention of many is Keto Now, a ketogenic supplement that was featured on the popular television show Shark Tank.
Keto Now: The Next Big Thing in Keto
Keto Now is a dietary supplement that claims to help users achieve ketosis more quickly and easily than by diet alone. Ketosis is a natural metabolic state in which the body burns fat for fuel instead of carbohydrates, leading to rapid weight loss and increased energy levels. Keto Now contains a blend of ingredients that are designed to support ketosis and provide the body with the nutrients it needs to stay healthy and energized while on a ketogenic diet.
One of the key ingredients in Keto Now is beta-hydroxybutyrate (BHB), a ketone body that the body produces during times of fasting or carbohydrate restriction. BHB helps to kickstart the body into ketosis, allowing users to start burning fat for fuel right away. By taking Keto Now, users can increase their blood ketone levels and stay in ketosis longer, leading to faster weight loss and increased energy levels.
Another important ingredient in Keto Now is MCT oil, which is a type of fat that is easily converted into ketones by the liver. This allows users to quickly increase their blood ketone levels and enter ketosis faster. MCT oil also has been shown to support brain health and improve cognitive function, making it an ideal supplement for those following a ketogenic diet.
Benefits of Keto Now
Users of Keto Now can expect to experience a wide range of benefits, including rapid weight loss, increased energy levels, and improved mental clarity. By supporting the body’s natural ability to enter ketosis, Keto Now can help users achieve their weight loss goals more quickly and easily than by diet alone. Additionally, the ingredients in Keto Now can help to reduce cravings for high-carb foods and keep users feeling satisfied and energized throughout the day.
One of the main benefits of Keto Now is its ability to help users maintain ketosis for longer periods of time. By taking Keto Now regularly, users can increase their blood ketone levels and stay in ketosis even when they have the occasional high-carb meal. This can help to prevent weight gain and keep users on track with their weight loss goals.
In addition to supporting weight loss, Keto Now can also help to improve overall health and well-being. By reducing inflammation in the body and supporting healthy blood sugar levels, Keto Now can help to reduce the risk of chronic diseases such as diabetes, heart disease, and cancer. The ingredients in Keto Now have also been shown to support digestive health and improve nutrient absorption, leading to better overall health and vitality.
FAQs about Keto Now
1. Is Keto Now safe to use?
Yes, Keto Now is made with all-natural ingredients that are safe for most users. However, it is always recommended to consult with a healthcare professional before starting any new supplement regimen, especially if you have any underlying health conditions.
2. How quickly can I expect to see results with Keto Now?
Results may vary, but many users report experiencing increased energy levels and weight loss within the first few weeks of taking Keto Now. For best results, it is recommended to follow a ketogenic diet and exercise regularly while taking Keto Now.
3. Can I take Keto Now if I am not following a ketogenic diet?
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While Keto Now is designed to support ketosis, it can still be beneficial for those not following a strict ketogenic diet. The ingredients in Keto Now can help to reduce cravings for high-carb foods and support weight loss, even if you are not in ketosis.
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Does Metformin Cause Weight Gain? In this informative video, we will discuss Metformin, a widely used medication for managing type 2 diabetes, and its effects on weight. We’ll cover how Metformin works to help control blood sugar levels and its impact on weight management. Many individuals are curious about whether this medication can lead to weight gain, and we will clarify this point. We will explore the potential benefits of Metformin in terms of weight stability and even modest weight loss for some patients. Additionally, we will address common side effects that may influence appetite during the initial phase of treatment. It’s important to understand how Metformin interacts with other medications and how it may help mitigate weight gain caused by those drugs. If you are currently taking Metformin or considering it as part of your diabetes treatment plan, this video will provide essential information to help you make informed choices. We encourage you to consult with your healthcare provider if you experience any unexpected changes in your weight while on this medication. Join us for this insightful discussion, and don’t forget to subscribe to our channel for more helpful content on diabetes management and medication. ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@Pharmaceutical-Insights/?sub_confirmation=1 #Metformin #Type2Diabetes #WeightManagement #BloodSugarControl #DiabetesTreatment #MedicationInfo #HealthTips #WeightLoss #InsulinSensitivity #AppetiteControl #DiabetesCare #ChronicIllness #PatientEducation #HealthyLiving #MedicationSideEffects About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.
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State Representative Josh Williams introduces legislation that would lower the cost of GLP-1s for Ohio state employees and legislators.
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Week 12 weigh in on Mounjaro 5mg. What a great 12 weeks it’s been and I feel transformed by the journey so far. Feeling excited and ready for Christmas without the looming fear of overeating.
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