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In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance. We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins. Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance. Access the full show notes for this episode: https://go.hubermanlab.com/Nya6k2f Pre-order Andrew's book, Protocols: https://go.hubermanlab.com/protocols Use Ask Huberman Lab, our chat-based tool, for summaries, clips, and insights from this episode: https://go.hubermanlab.com/tqqZoQT *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Eight Sleep: https://eightsleep.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Dr. Craig Koniver* Koniver Wellness: https://koniverwellness.com Koniver Aesthetics: https://koniveraesthetics.com Instagram: https://www.instagram.com/koniverwellness LinkedIn: https://www.linkedin.com/in/craig-koniver-md-4bb100126 *Timestamps* 00:00:00 Dr. Craig Koniver 00:04:52 Sponsors: Joovv & BetterHelp 00:07:40 What is a Peptide? 00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health 00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation 00:18:43 BPC-157, Inflammation 00:23:27 BPC-157, Injection & Oral Forms; Injury Repair 00:28:43 Sourcing, Anabolic Steroids, Testosterone 00:34:48 Black & Gray Market, Compounding Pharmacies, Purity 00:38:20 Sponsor: AG1 00:39:51 Partnering with a Physician, LPS 00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses 00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone 00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides 00:58:45 Sponsor: Function & Eight Sleep 01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health 01:05:16 Prescriptions, Physicians & Trust 01:14:09 Agency in Your Health 01:17:13 MK-677, Appetite 01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing 01:21:10 Methylated B Vitamins, Homocysteine 01:24:47 Peptides for Sleep, Pinealon, Epitalon 01:31:03 Glycine, Liver Detoxification; Dosage 01:37:19 GLP-1, Compounding Pharmacies 01:39:03 Stem Cell Therapy, PRP 01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health 01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses 01:50:20 Covid, NAD Infusion, NMN & NR Supplements 01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR 02:07:53 PT-141, Vyleesi, Libido; Nausea 02:10:57 FDA Approval & Removal, Pharmaceutical Companies 02:20:17 Positivity, Mindset & Health 02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Health #Peptides Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

Bonnie Chapman Reveals The Weightloss Drug That Changed Her Life

With the increasing prevalence of obesity and related health conditions, there is a growing demand for effective weight loss treatments. One recent development in this field is the approval of semaglutide, a medication originally used for treating type 2 diabetes, for weight loss. However, there are different formulations of semaglutide available, each with its own specific indications and dosages. In this article, we will explore which semaglutide formulation has been approved for weight loss and how it works to help individuals achieve their weight loss goals.

What is Semaglutide and How Does it Work?

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of GLP-1, a hormone in the body that helps regulate blood sugar levels and appetite. By activating the GLP-1 receptors in the brain, semaglutide can increase feelings of fullness and reduce food intake, leading to weight loss.2025 New Year New Me Newyearsresolution Newyear Happynewyear Transformation Weightloss Arnold

In addition to its effects on appetite regulation, semaglutide also helps reduce blood sugar levels by stimulating insulin production and decreasing glucagon secretion. This dual mechanism of action makes semaglutide an effective treatment for both weight loss and diabetes management.

Studies have shown that semaglutide can lead to significant weight loss when used as a treatment for obesity. In clinical trials, participants who took semaglutide experienced greater weight loss compared to those who took a placebo. This has led to the approval of semaglutide for weight loss in certain populations.

Which Semaglutide Formulation is Approved for Weight Loss?

The semaglutide formulation that has been specifically approved for weight loss is known as Wegovy. Wegovy is a higher dose formulation of semaglutide that is administered once weekly via subcutaneous injection. It is indicated for chronic weight management in adults with obesity or overweight individuals with at least one weight-related comorbidity.





Wegovy is intended to be used in conjunction with a reduced-calorie diet and increased physical activity for long-term weight management. It is not meant for short-term weight loss or as a temporary solution. Individuals who are interested in using Wegovy for weight loss should consult with their healthcare provider to determine if it is a suitable option for them.

Like any medication, Wegovy may cause side effects, including nausea, vomiting, diarrhea, and constipation. It is important for individuals to be aware of the potential risks and benefits of using Wegovy for weight loss and to follow their healthcare provider’s guidance for safe and effective use.

FAQ: Common Questions About Semaglutide for Weight Loss

1. Is Wegovy the only semaglutide formulation approved for weight loss?

Yes, currently Wegovy is the only semaglutide formulation that has been approved by the FDA for weight loss. Other formulations of semaglutide are primarily used for the treatment of type 2 diabetes.

2. How long does it take to see results with Wegovy?

Individuals may start to see weight loss results within a few weeks of starting treatment with Wegovy, but optimal results are typically seen after several months of consistent use.

3. Can anyone use Wegovy for weight loss?

Wegovy is specifically indicated for adults with obesity or overweight individuals with at least one weight-related comorbidity. It is important to consult with a healthcare provider to determine if Wegovy is a suitable treatment option for your weight loss goals.

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Recent studies have uncovered troubling psychological side effects from GLP-1 medications like Ozempic and Mounjaro—anxiety, depression, even suicidal thoughts. These drugs offer weight loss through appetite suppression, but what happens to those who rely on food for emotional comfort or stress relief? Without emotional coping tools in place, the consequences can be severe. Your emotional wellbeing matters just as much as your physical health. Before starting GLP-1 meds, consider your emotional readiness and therapeutic support systems. 📥 Free GLP-1 reflection guide: 👉 https://aceds-online.thinkific.com/products/digital_downloads/glp-1-reflection-handout 📞 Book a free enquiry call: 👉 https://calendly.com/aceds/30min 🌐 Learn more: https://www.aceds.co.uk 📱 Contact: 01202 122796 🎥 Subscribe for more guidance: 👉 https://www.youtube.com/@ClinicoNutrition?sub_confirmation=1 #MentalHealthAwareness #GLP1Risks #EatingDisorderRecovery #OzempicAwareness #TherapeuticSupport #ClinicoNutrition