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GLP-1 medications like Ozempic are EVERYWHERE—hailed as miracle weight loss solutions and crucial tools in managing type 2 diabetes. But what’s really happening inside your body when you take these meds? And are we ignoring some serious dangers in the pursuit of quick results? In this episode of Straight Up With Steph, host Stephanie Botts sits down with renowned pharmacologist Tom Viola to get “straight up” about the facts, myths, and hidden risks of this trending weight loss solution. Whether you’re a healthcare provider, considering GLP-1s for yourself, or just want the real scoop, this discussion is unfiltered, eye-opening, and practical. Tune in to discover: 💊 What GLP-1s (like Ozempic) actually are and how they revolutionized diabetes and weight loss treatments 💊 How these drugs went from serving diabetics to being used by nearly everyone wanting to lose weight 💊 Why so many patients risk major side effects—like muscle loss, GI problems, kidney and liver stress, and “Ozempic face” 💊 The dark world of black-market prescriptions: why you should never buy these meds from unauthorized sources 💊 How drastic weight loss from GLP-1s can lead to “skinny fat,” muscle deterioration, and future health issues 💊 The surprising link between these medications and mental health concerns, including increased depression and suicidal thoughts 💊 What dental professionals are noticing in patients’ mouths—and why it matters for your overall health If you—or someone you care about—are thinking about taking GLP-1s, or you’re a healthcare professional seeing this trend in your clinic, this episode is a must-watch! About Tom Viola: With over 30 years’ experience as a board-certified pharmacist, clinical educator, professional speaker, and published author, Tom Viola, R.Ph., C.C.P. has earned his national and international reputation as the go-to specialist for making pharmacology practical and useful for all members of the dental team. Tom has presented over 1000 informative, humorous and engaging continuing education seminars and webinars to dental professionals internationally since 2001. Connect with Tom: Website: https://www.tomviola.com/ Email: [email protected] Facebook: https://www.facebook.com/PharmacologyDeclassified/ Instagram: https://www.instagram.com/pharmacologydeclassified Timestamps: 00:00 Introduction of Tom Viola 02:01 The History of GLP-1s and Insulin Resistance 06:45 The Problem with Insulin 11:10 How Do GLP-1s Work? 16:40 How to Get GLP-1s like Ozempic 20:15 The Effects of GLP-1s on Weight Loss 23:14 The Problem with Ozempic Counterfeits 29:38 Risks of Stopping Ozempic and Regaining Weight 30:42 Muscle Loss as an Effect of Ozempic/ Other GLP-1s 40:42 Side Effects of GLP-1s that Dental Clinicians Should Know 46:08 Suicidal Thoughts, Depression, and Anxiety as a Result of Using GLP-1s 50:10 What to Know When Your Patient is Taking a GLP-1 54:27 How to Connect with Tom Viola Disclaimer: The opinions expressed by guests on this podcast are their own and do not necessarily reflect the views of Polished Posture. The information shared in this podcast is for educational and entertainment purposes only and should not be considered medical advice. Always consult a qualified healthcare professional for any health concerns or before making significant lifestyle changes. To connect with me: ➡️Instagram: https://www.instagram.com/steph.polishedposture 💻My Website: https://www.polishedposture.net 📨Email: [email protected] 🛒My Store: https://polishedposture-shop.myshopify.com 💌Newsletter signup: https://www.polishedposture.net/subscribe Thank you for watching!

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Obesity is a major health concern that affects millions of people worldwide. While diet and exercise are the cornerstones of weight loss, some individuals may benefit from additional interventions to help them achieve their goals. Semaglutide, a medication originally developed for the treatment of type 2 diabetes, has recently gained attention for its potential use in weight loss. In this article, we will take an in-depth look at what semaglutide does for weight loss and how it may help individuals struggling with obesity.

Semaglutide Mechanism of Action

Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 is a hormone that is produced in the gut in response to food intake. It plays a crucial role in regulating blood sugar levels by promoting the secretion of insulin and inhibiting the release of glucagon. In addition to its effects on blood sugar, GLP-1 also acts on the brain to reduce appetite and increase feelings of fullness.

Semaglutide mimics the effects of GLP-1, leading to increased insulin secretion, decreased glucagon release, and decreased appetite. By activating GLP-1 receptors in the brain, semaglutide helps individuals feel more satiated after meals, making it easier for them to stick to a calorie-restricted diet.

Furthermore, semaglutide also slows down the emptying of the stomach, which can help reduce the rate at which food is absorbed into the bloodstream. This effect may help prevent blood sugar spikes and promote weight loss by reducing overall calorie intake.

Benefits of Semaglutide for Weight Loss

Several clinical trials have investigated the use of semaglutide for weight loss in individuals with obesity. These studies have shown that semaglutide can lead to significant reductions in body weight when used in combination with diet and exercise. In fact, some trials have reported weight loss of up to 15% of initial body weight in individuals treated with semaglutide.

In addition to weight loss, semaglutide has been shown to improve various metabolic parameters, such as blood sugar levels, blood pressure, and cholesterol levels. These improvements can have a positive impact on overall health and reduce the risk of developing obesity-related complications, such as type 2 diabetes and heart disease.

Furthermore, semaglutide has also been found to improve quality of life in individuals with obesity. By helping individuals achieve their weight loss goals, semaglutide can boost self-esteem, confidence, and overall well-being.

Potential Side Effects of Semaglutide

While semaglutide is generally well-tolerated, like any medication, it can cause side effects in some individuals. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.

In rare cases, semaglutide can cause more serious side effects, such as pancreatitis, thyroid tumors, and kidney problems. It is important to discuss the risks and benefits of semaglutide with your healthcare provider before starting treatment. Your healthcare provider can help you decide if semaglutide is the right choice for you based on your individual medical history and risk factors.

Overall, the benefits of semaglutide for weight loss are promising, but it is essential to use this medication under the guidance of a healthcare professional to ensure safe and effective treatment.

Conclusion

In conclusion, semaglutide is a promising medication for weight loss that works by mimicking the effects of GLP-1 in the body. By reducing appetite, slowing stomach emptying, and promoting feelings of fullness, semaglutide can help individuals achieve their weight loss goals and improve overall health. While semaglutide has been shown to be effective in clinical trials, it is essential to use this medication under the supervision of a healthcare provider to minimize the risk of side effects and maximize the benefits of treatment.

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