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Metformin is a commonly prescribed diabetes drug, but it is also popular among biohackers and life extensionists who take it for what they believe to be its longevity benefits. While this use is still being investigated, new studies indicate that taking metformin may have some drawbacks, including a new study indicating metformin decreases the gains in respiratory performance brought on by exercise. Previous studies have shown that respiratory fitness, as defined by an increase in VO2max, may have an impact in preventing hyperglycemia and type 2 diabetes, although the associated weight loss is also likely to contribute. The researchers of this study sought to determine if metformin impairs gains in VO2max the way it impairs muscle growth, as has been suggested by previous studies. This study focused on the people most likely to be taking metformin: people with metabolic syndrome. A total of 72 overweight or obese men and women with an average age of 53 were separated based on whether they were taking metformin or not. 63 of these people were able to complete 16 weeks of high-intensity interval training, which focuses on exercise sessions that maximize heart rate in order to increase cardiovascular and respiratory performance. Metabolic syndrome, respiration, and blood glucose were among the biomarkers assessed. However, this was not a placebo-controlled study, and the baseline characteristics of the two groups were different. Both groups were positively affected in every measurement of VO2max, but the researchers' hypothesis was correct: the improvements brought on by the exercise in this respect were significantly blunted in people taking metformin. While there was no significant difference in baseline measurements, the people who did not take metformin had better respiratory performance than the people who did. Regardless of these results, it may be unwise to cease taking metformin if you were prescribed it by your doctor. As an inhibitor of blood glucose, metformin is prescribed for reasons that often outweigh the concerns raised in this study - but you should certainly ask your doctor any questions you may have. But this study does illustrate a potential issue with metformin, particularly when it comes to people who would use it to augment their health, rather than to treat an existing condition. Previous studies do show that at least some cohorts do not experience reduced mortality. However, many believe that this drug is still worth exploring as a longevity drug. I am very much looking forward to the results of this study, and it should answer many lingering questions that we currently have. SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Effects of chronic metformin treatment on training adaptations in men and women with hyperglycemia: A prospective study - https://onlinelibrary.wiley.com/doi/10.1002/oby.23410 Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study - https://diabetesjournals.org/care/article-abstract/44/12/2775/138471/Effect-of-Metformin-and-Lifestyle-Interventions-on Targeting Aging with Metformin (TAME) Trial - https://www.afar.org/tame-trial FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Stock footage & Images : Videoblocks.com, Shutterstock.com Robbie M / Shutterstock.com Music: "Elastic Vibe" by Ziv Moran PRODUCTION CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Host, Producer & Editor - Ryan O’Shea Writer - Josh Conway Art - Mattijs Vonk, Tim Maupin Executive Producer - Keith Comito #Metformin #Exercise #Longevity
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Did you know GLP-1 is naturally made in the body? Did you know you can increase GLP-1 just by changing the foods you eat? Watch my video here to learn more. For an in depth session on diet and GLP-1, watch the linked video "Natures Ozempic : Eat These Foods to Naturally Increase GLP-1" Eating certain foods are an easy way to manage blood sugar and make living with diabetes, prediabetes, or PCOS easier. #fiber #prediabetes #life #wellness #wellbeing #fiber #resistantstarch
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Since its inception, the popular television show Shark Tank has been a platform for aspiring entrepreneurs to pitch their business ideas and products to a panel of wealthy investors. Many successful businesses have emerged from the show, including the now-famous Keto Pills. The journey of Keto Pills from concept to reality is a fascinating story of dedication, perseverance, and strategic planning.
The Pitch on Shark Tank
The creators of Keto Pills appeared on Shark Tank in Season 7, episode 4, with their innovative weight loss product. Their pitch was met with skepticism from some of the investors, but they ultimately struck a deal with one of the sharks. This marked the beginning of Keto Pills’ journey from a concept to a fully realized product.
During their pitch, the creators of Keto Pills emphasized the science behind their product, highlighting the effectiveness of the keto diet for weight loss. They also discussed the market demand for a convenient and reliable supplement to support the keto diet. These key points resonated with the investors and set the stage for the successful launch of Keto Pills.
Following their appearance on Shark Tank, the creators of Keto Pills worked tirelessly to bring their product to market. They conducted extensive research and development to perfect the formula for their pills, ensuring that they delivered maximum results for their customers. This dedication to quality and effectiveness set Keto Pills apart from other weight loss supplements on the market.
Bringing Keto Pills to Market
After securing a deal on Shark Tank, the creators of Keto Pills faced the daunting task of bringing their product to market. They navigated the challenges of production, distribution, and marketing, leveraging their resources and expertise to overcome obstacles along the way. Their persistence and strategic planning were instrumental in turning Keto Pills from a concept into a reality.
One of the key strategies that the creators of Keto Pills employed was building partnerships with retailers and online platforms to ensure widespread availability of their product. They also implemented a targeted marketing campaign to reach their target audience of individuals following the keto diet. These efforts helped Keto Pills gain traction in the competitive weight loss supplement market.
As Keto Pills gained momentum in the market, the creators continued to innovate and expand their product line. They introduced new variations of their pills to cater to different dietary preferences and health goals, further solidifying Keto Pills’ reputation as a trusted and effective weight loss supplement. This commitment to product development and customer satisfaction has been essential to Keto Pills’ continued success.
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Since its debut on Shark Tank, Keto Pills has had a significant impact on the weight loss supplement industry. The product has garnered a loyal following of customers who have achieved impressive results following the keto diet with the support of Keto Pills. Many users have shared their success stories and testimonials, praising the effectiveness and convenience of the product.
Furthermore, Keto Pills has inspired a wave of innovation in the weight loss supplement market, prompting other companies to develop their own versions of keto pills. This competition has led to a greater focus on quality and effectiveness in the industry, benefiting consumers who are seeking safe and reliable weight loss solutions. Keto Pills’ success serves as a testament to the power of entrepreneurship and innovation in transforming ideas into reality.
In conclusion, the journey of Keto Pills from a concept pitched on Shark Tank to a successful and widely recognized weight loss supplement is a testament to the creators’ vision, dedication, and strategic planning. The impact of Keto Pills on the weight loss supplement industry and its loyal customer base is a testament to the product’s effectiveness and quality. As Keto Pills continues to evolve and expand its product offerings, it remains a shining example of entrepreneurship and innovation in the competitive world of health and wellness products.
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