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What do patients who use GLP-1s and patients who undergo Bariatric Surgery have in common? Weight-regain after 1-2 years. Why have these approaches to weight-loss proven so unsustainable? Want to learn more about Sustainable Weight Loss? Visit us at https://toward.health

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Dr. James Stirrett explains the why ozempic, semaglutide, wegovy, zepbound, and other similar GLP-1 medications are anti-inflammatory.

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Weight loss isn’t just about willpower — sometimes, the right support makes all the difference. Wegovy and Rybelsus are two modern weight loss medications that work on your hormones to: · Control appetite · Improve insulin sensitivity · Help shed stubborn weight But keep in mind — these are not magic pills. They work best when combined with healthy lifestyle changes and taken under medical supervision. · Not for everyone. Not a shortcut. · Often effective for people with obesity or diabetes. Considering weight loss medicines? Always consult your doctor before starting to ensure they’re right for you. #weightlossjourney #wegovy #rybelsus #weightlosstips #hormonalhealth #endocrinology #healthyweightloss

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Optiplex Keto Gummies is a weight loss supplement that first received tremendous attention when it appeared on the popular television show Shark Tank. The company pitched their gummies for weight loss, which would supposedly provide customers with the benefits of the keto diet in a convenient and tasty gummy form. The personalised pitches made by the founders of Optiplex Keto Gummies on Shark Tank was quite impressive, where they convinced the Sharks that their keto gummies were not only effective, but had already garnered positive reviews from their consumers. The episode left me pondering whether the two founders truly came up with something amazing, which would greatly ease one’s weight loss journey, or if they were just capitalising on the current dieting trends by adding all the buzzwords all over their products.

The Shark Tank Pitch

Patrikos pitched the founders’ story about their product to the sharks of Shark Tank, describing a product that would help people lose weight while improving their health. According to Patrikos, this product was especially formulated with ingredients that promoted the consumer’s natural transition into ketosis. The sharks were receptive to the founders’ success stories and to pitching the potential market for their product.

The ease of use of Optiplex Keto Gummies was one of its top promotional points: unlike a ketogenic diet, which involves careful meal planning and keeping track of foods, the customer can eat the gummies and still experience the benefits of feeling ‘more energetic and lively’, having ‘reduced appetite to eat’ and regaining ‘good and great mental focus’.

Following their pitch, the sharks asked the founders to present data proving that their product actually works. The founders referred to clinical studies and customer testimonials to prove that the gummies are effective. Though the sharks appeared somewhat skeptical, several of them offered investment in the Keto Optiplex gummies, sensing the opportunity to change the health and wellness industry.

The Aftermath

After making an appearance on Shark Tank, Optiplex Keto Gummies were flooded with requests as people vied to try the product that the judges lauded as a potential million dollars venture. These gummies boasted the claim of being keto-friendly, and many Shark Tank viewers wanted to know what all the fuss was about. With increased interest came a flood of orders, which started earning Optiplex Keto Gummies even more positive publicity.

However, as more people tried the product, negative reviews began to surface about how it performed.

Some reviewed they had lost significant amounts of weight and experienced more energy as a result of taking the Optiplex Keto Gummies. Others said they didn’t feel any different. One even complained about inconsistent gummies, with one having a bitter aftertaste and others melting faster. Others were worried about long-term consequences associated with ingesting such a high dose of exogenous ketones in a gummy.

Despite the fact the Optiplex Keto Gummies was safely gaining attention through success stories, health experts criticised the dependence on a supplement to achieve the results as unrealistic, saying that long-term results came down to diet and exercise providing a holistic approach to weight management, rather than an easy short cut to success through a gummy.
The Optiplex Keto Gummies has not been in the spotlight recently. It seems that researches on the safety and effectiveness of Optiplex Keto Gummies are still ongoing.

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Dermatologist Dr Dray responds to Halle Berry's claims about her keto diet and lifestyle for anti aging. In this video I discuss potential skin benefits of the keto diet. My response to Natalie Portman https://youtu.be/X_HJY8jq6ew My response to Jennifer Aniston https://youtu.be/wx_d-DCWL1A My response to Jessica Chastain https://youtu.be/u3Hn-grs3ZI My response to JLo https://youtu.be/mwIA0jRSdaY My response to Asthon Kutcher & Mila Kunis https://youtu.be/r9sZKwbyVn8 My video on acanthosis nigricans https://youtu.be/GpQpBTAsS7c My video on the effects of alcohol on skin https://youtu.be/snxLadfgyxY My video on dairy and skin https://youtu.be/2oX65CPofH8 My video on sugar and skin https://youtu.be/b4uoMxbN1hI My video on the keto diet and skin https://youtu.be/lk6_QVrURe4 My video on diet for clear skin https://youtu.be/fFAO8CH0bGY My video on the best foods for collagen https://youtu.be/w_Dq1cW60AM My video on the worst foods for collagen https://youtu.be/ZDpSOniJIVA References Castellana M, Conte E, Cignarelli A, et al. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: a systematic review and meta-analysis. Rev Endocr Metab Disord. 2020;21:5-16. Hu Y, Zhu Y, Lian N, et al. Metabolic syndrome and skin diseases. Front Endocrinol (Lausanne). 2019;10:788. Castaldo G, Rastrelli L, Galdo G, et al. Aggressive weight-loss program with a ketogenic induction phase for the treatment of chronic plaque psoriasis: a proof-of-concept, single-arm, open-label clinical trial. Nutrition. 2020;74:110757. Castaldo G, Pagano I, Grimaldi M, et al. Effect of very-low-calorie ketogenic diet on psoriasis patients: a nuclear magnetic resonance-based metabolomic study. J Proteome Res. 2021;20:1509-1521. Milder J, Liang L-P, Patel M. Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet. Neurobiol Dis. 2010;40:238-244. Kubo E, Chhunchha B, Singh P, et al. Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress. Sci Rep. 2017;7:14130 Pinto A, Bonucci A, Maggi E, et al. Anti-oxidant and anti-inflammatory activity of ketogenic diet: new perspectives for neuroprotection in Alzheimer's disease. Antioxidants (Basel). 2018;7:63. Youm Y-H, Nguyen KY, Grant RW, et al. The ketone metabolite beta hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat Med. 2015;21:263-269. Fomin DA, McDaniel B, Crane J. The promising potential role of ketones in inflammatory dermatologic disease: a new frontier in treatment research. J Dermatol Treat. 2017;28:484-487. Alshaya MA, Turkmani MG, Alissa AM. Prurigo pigmentosa following ketogenic diet and bariatric surgery: a growing association. JAAD Case Rep. 2019;5:504-507. FTC: This video is not sponsored. 💜Follow me on liketoknowit https://www.liketoknow.it/drdrayzday 💜Social media Instagram @drdrayzday Pinterest https://www.pinterest.com/drdrayzday/ Facebook @DrDrayzDay Twitter: @drdrayzday 📪Mail: PO Box 542234 Houston, TX 77254 Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.

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Dr Anne Peters discusses the need for lifestyle changes in combination with antiobesity medications for weight loss. https://www.medscape.com/viewarticle/maintaining-weight-loss-glp-1s-needs-lifestyle-changes-2024a1000ld0?src=soc_yt -- TRANSCRIPT -- Nearly every patient I start on incretin therapy for weight loss asks me the same question, which is, will I have to stay on this forever? The answer is probably yes, but I think it’s much more nuanced than that because A) forever is a long time and B) I think there are various ways to approach this. I want people to start just saying, let’s see how this works, because not everyone’s going to lose the same amount of weight or respond in the same way. I say let’s try it, but don’t stop it suddenly. If we decide at some point you don’t need quite the same dose, we can reduce the dose and maybe even reduce the frequency of giving it, but you don’t want to stop cold turkey because you may well regain the weight, and that’s obviously not our desired outcome. There have been multiple clinical trials in which people started on an incretin hormone, either a glucagon-like peptide 1 (GLP-1) receptor agonist or a dual hormone, and they’ve actually shown that stopping it and then continuing patients on a placebo vs active drug results in continued weight gain over time vs either weight maintenance or weight loss when they remain on the incretin hormone. Clearly, on average, people will regain the weight, but that isn’t always true. One of the things I think is really important is that, from the get-go on starting on these hormones, people start working with a lifestyle plan, whether it’s working with a coach or an online program. However they approach this, it’s important to start changing habits and increasing exercise. I can’t say how important this is enough, because people need to increase their physical activity to enhance the benefits of these agents and also to help retain lean body mass. I don’t want people losing a large amount of lean body mass as they go through the process of weight loss. I set the stage for the fact that I expect people to adhere to a lifestyle program, and maybe losing weight with the medications is going to help them do even better because they’re going to see positive outcomes. When they get to the point of weight maintenance, I think we need to reinforce lifestyle. I either go down on the dose given weekly or I start having patients take the dose every other week, for instance, as opposed to every week, and then sometimes every month. Depending on the patient, I get them potentially to a lower dose, and then they’re able to maintain the weight as long as they improved their lifestyle along with the changes in the medication. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/maintaining-weight-loss-glp-1s-needs-lifestyle-changes-2024a1000ld0?src=soc_yt