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이전에 사용되던 주사형 비만치료제와 차별화된 새로운 경구 비만치료제, Orforglipron에 대한 소식을 전하려 합니다. Orforglipron은 기존의 Wegovy, Mounjaro, Saxenda 등과 같은 GLP-1 agonist 기반의 약이지만, 가장 큰 차이점은 이 약이 복용형이라는 점입니다. 주사를 매일 또는 일주일에 한 번씩 맞는 것을 꺼려하는 환자분들에게 이 약은 매우 큰 도움이 될 것입니다. 약의 효과에 대해 말씀드리자면, 36주간 관찰한 결과 최대 용량을 복용했을 때 체중감소율이 14.7%에 달하였고, 이는 약 80kg인 사람이라면 약 11-12kg의 체중감소를 의미합니다. 또한, 흥미로운 점은 이 체중 감소 추세가 36주에서도 계속 이어지고 있으며, 이는 주사형 약물과 비교해도 결코 뒤지지 않는 효과입니다. 부작용에 관해서는 GLP-1 agonist 약들과 유사한 수준이었으며, 대부분의 참여자들이 약 복용에 문제가 없었다는 결과를 보여주었습니다. 마지막으로, 이 약이 곧 FDA의 승인을 받을 것으로 기대되며, 그렇게 되면 새로운 사실들을 영상을 통해 계속 공유하도록 하겠습니다.

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Stacey Silver of St. Mary's Medical Center is interviewed on how to lose belly fat.