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This Harvard Medical School Continuing Education video examines the key question: Do you know when to use an SGLT2 inhibitor versus a GLP-1 receptor agonist with your patients?   Dr. Lee-Shing Chang, MD, an endocrinologist at Brigham and Women’s Hospital in Boston, Massachusetts, reviews compelling reasons to choose an SGLT2 inhibitor (SGLT2i) vs a GLP-1 receptor agonist (GLP-1 RA). Medical indications, comorbidities and side effects, and the administration of SGLT2i and GLP-1 RA are discussed and compared. 00:00 | Introduction 00:57 | Medical indications for SGLT2i and GLP-1 RA 03:00 | Comorbidities and side effects of SGLT2i and GLP-1 RA 6:07 | Administration differences between SGLT2i and GLP-1 RA This video was peer reviewed by Dr. Jonathan Salik, TMD, MHPEd, Instructor of Medicine, Massachusetts General Hospital; and Dr. Sugantha Sundar, MD, Assistant Professor of Anesthesia, Beth Israel Deaconess Medical Center, to validate the quality and accuracy of the content.   References: Das SR, et al. 2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients with Type 2 Diabetes. J Am Coll Cardiol. 2020: 76(9): 1117-45. Published 2020 Sep 1. Accessed 22 Jan 2022.     Notice: At this time, the content in this video is not accredited.

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The Ultimate GLP-1 Friendly Salty Snack Taste Test In this episode of The Downsized, hosts Christopher and Laraine Durham delve into the world of GLP-1 friendly salty snacks. For their latest taste test, they sample a variety of protein-packed chips and pretzels, evaluating everything from Quest's tortilla-style protein chips to Lenny and Larry's high-protein pretzels. Christopher and Laraine discuss each product's nutritional value, flavor, and practicality as a snack option for those on GLP-1 medications. They cover the brands, flavors, and textures, providing honest reviews including which snacks they would buy again and which ones were less appealing. The couple also shares their personal weight loss journeys, emphasizing the importance of protein in their diets to maintain muscle mass and fullness. This episode is aimed at viewers managing obesity and looking for healthier snack alternatives that fit within their dietary plans. DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store BOOK THE DOWNSIZED AT SEA CRUISE: https://thedownsized.org/downsized-at-sea-2025/ DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. 00:00 Introduction to The Downsized 00:05 Overview of Today's Taste Test 00:36 Meet the Laraine & Christopher 02:53 Importance of Protein in GLP-1 Diets 05:12 Quest Tortilla Style Protein Chips Review 09:13 Wild Protein Chips Review 11:30 Legendary Protein Chips Review 14:33 Lenny and Larry's Protein Pretzels Review 18:19 Quest Cheese Crackers Review 20:59 Final Thoughts and Recommendations 24:26 Conclusion and Upcoming Reviews

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