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MEDICAL ANIMATION TRANSCRIPT: La semaglutida es un medicamento que se utiliza para ayudar a perder peso a las personas con sobrepeso u obesidad. Para comprender cómo actúa la semaglutida en la pérdida de peso, es importante saber qué es el GLP-1. El GLP-1, o péptido similar al glucagón tipo 1, es una proteína que se produce en varias partes del cuerpo, como el tronco encefálico y los intestinos. Al comer, el tubo digestivo descompone los alimentos en nutrientes. Uno de ellos es un azúcar llamado glucosa. La pared del tubo digestivo absorbe la glucosa y la libera en el torrente sanguíneo. La glucosa en el tubo digestivo hace que éste libere GLP-1. El GLP-1 hace que los alimentos salgan del estómago más despacio. El tronco encefálico también puede liberar GLP-1. Esto puede deberse al estrés o a una comida abundante. El GLP-1 actúa sobre las zonas del cerebro que regulan el hambre, como el hipotálamo, para hacerle sentir menos hambre. Los medicamentos con semaglutida forman parte de una clase de fármacos denominados agonistas del GLP-1. Actúan como el GLP-1 que produce el cuerpo. Por ejemplo, los agonistas del GLP-1 ayudan a que los alimentos salgan más despacio del estómago. Dado que esto aumenta la sensación de saciedad, puede ayudarle a comer menos. La semaglutida también puede actuar sobre las zonas cerebrales que regulan el hambre para disminuir el apetito. Para ayudarle a alcanzar su objetivo de pérdida de peso, su médico puede crear un plan de tratamiento que incluya una dieta baja en calorías y grasas, así como más ejercicio. La semaglutida para la pérdida de peso es una inyección líquida que se presenta en una pluma precargada. Se inyecta en el abdomen, el muslo o la parte superior del brazo una vez a la semana el mismo día. Siga cuidadosamente las instrucciones para aplicar la inyección de semaglutida. Es probable que empiece con una dosis más baja de semaglutida durante algunas semanas. Después, su médico podría aumentar la dosis con el tiempo. Los efectos secundarios más frecuentes de la semaglutida son problemas estomacales e intestinales de leves a moderados, como: náuseas, vómitos y diarrea. Algunos efectos secundarios pueden ser más graves. Si presenta alguno de estos síntomas, póngase en contacto con su médico: taquicardia; problemas para respirar o tragar; hinchazón de piernas, tobillos o pies; menor producción de orina; dolor de estómago que puede extenderse a la espalda; piel u ojos amarillentos; fiebre; confusión o somnolencia; ansiedad, irritabilidad u otros cambios de humor; cambios en la visión, entre estos, visión borrosa; sensación de mareo, vértigo, temblores o nerviosismo; dificultad para hablar; o erupción cutánea, comezón o hinchazón de la cara, boca o garganta. Para obtener más información sobre la semaglutida para bajar de peso, hable con su médico.

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