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00:00 - Intro 00:16 - Ozempic & GLP-1 Drugs Cut Death Risk by 30% for Obesity & Type 2 Diabetes | JAMA Study Explained 05:06 - GLP-1RAs May Reduce Dementia & Stroke Risk: New Study Reveals 1. Ozempic & GLP-1 Drugs Cut Death Risk by 30% for Obesity & Type 2 Diabetes | JAMA Study Explained A groundbreaking study published in JAMA reveals that drugs like Ozempic (semaglutide) and Mounjaro (tirzepatide) reduce the risk of death by 30% in people with obesity and type 2 diabetes. These GLP-1 agonist drugs also lower the risk of strokes by 19% and dementia by 37%. In this video, we break down the key findings of the study, explain how these drugs work beyond blood sugar control, and discuss the potential financial implications for employers and patients. If you or someone you know is managing obesity and diabetes, this video is a must-watch! Key Topics Covered: - What are GLP-1 agonists? - How do drugs like Ozempic and Mounjaro reduce mortality? - The link between GLP-1 drugs, strokes, and dementia. - Cost considerations and future predictions for these medications. - What this means for the 2/3 of Americans affected by obesity. Stay informed and take control of your health. Don’t forget to like, share, and subscribe for more updates on medical breakthroughs and health tips! 2. GLP-1RAs May Reduce Dementia & Stroke Risk: New Study Reveals A new study shows that popular weight loss medications like Ozempic and Mounjaro may lower dementia and stroke risks in adults aged 60+. The research followed 60,000 participants over seven years, highlighting benefits for older adults, women, and those with BMI 30-40. Experts caution that further studies are needed to confirm long-term neuroprotective effects, while noting the study's limitations in follow-up duration. Key findings include reduced risks of neurodegenerative and cerebrovascular diseases, though results vary by dementia type. Explore how these drugs could impact brain health and aging.

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Dieting is now going through a great period of revolution; with the powerful combination of keto and apple cider vinegar, there is a new product on the market for those who wish to lose weight. The new Keto ACV from Shark Tank can quickly change your life and help you gain new health rewards. We will discuss the Keto ACV science, its benefits and the way it became Shark Tank’s hit phenomenon.

What is Keto ACV?

The Keto ACV dietary supplement blends the power of the keto diet with that of apple cider vinegar for greater results. Fundamentally, the ketogenic diet is a low-carb, high-fat eating plan, which promotes quicker weight loss. It optimizes a person’s eating habits, thus providing numerous health benefits to them. Various studies have already confirmed the effectiveness of the keto diet in weight loss and improvement of overall health. It implies that following this plan, an individual gets a decent portion of nutrients. Moreover, apple cider vinegar has long been used as a health-promoting drink due to its multiple advantages related to weight loss, digestion, and metabolism. The Keto ACV dietary supplement represents an easy way to combine these powerful ingredients and assist users in their efforts to achieve weight loss.

Keto ACV, taken as directed, will place the body in the state of ketosis – that is, it will undergo a chemical reaction where fat itself is burned for fuel instead of carbohydrates. This translates to a rapid weight loss, as well as increased energy levels for the important things in life. The apple cider vinegar found in Keto ACV will also regulate blood sugar level, improve digestion, and reduce inflammation in the body. What this means is that if you are seeking to achieve your fitness goals, Keto ACV is a complete package which can benefit you.

Its quality, which is proven by the fact that it has been featured on Shark Tank, has earned it a reputation as the product to trust with your health. Many people who have included Keto ACV in their diet have reported that, after a few weeks, they have dropped pounds of unwanted weight, increased their energy and improved the overall condition of their bodies. It is no wonder that this acv Keto has become widely used by dieting people.

How does Keto ACV work?

Keto ACV provides the body with a significant amount of ketones by putting the body into ketosis. During ketosis, the body starts using its own fat cells for fuel instead of depending on carbohydrates for fuel without providing any negative side effects. This can lead to a very drastic decrease in weight and helps the user to enjoy a healthy increase in energy levels due to the use of fat as a fuel source. Along with the keto in Keto ACV, apple cider vinegar regulates blood sugar levels which could help improve many major health factors. Additional benefits include aiding in the digestive process by breaking down protein and preventing inflammation throughout the body.

If you take it as suggested on the course of the day, then Keto ACV helps to break through any stuck fat storage and weight loss stagnation. ALL the health benefits of your apple cider vinegar, as well as keto-friendly ingredients combined in the form of this supplement, nourish your body. If you are interested in losing weight and do not want to give up slowly without seeing any change, we advise you to these products. It can be used by both novice consumers of ketogenic foods and those who want to enhance the effect of keto supplements. Keto ACV is a fat-burning supplement known for its safety and high efficacy.

Conclusion:
Keto ACV is a natural approach to weight loss that is safe, effective, and easy to maintain. It is a great way for those looking to improve their health and well-being to lose weight in an all-natural way. With its scientifically proven formula, Keto ACV can help you to shed pounds and maintain your ideal weight in an easy and convenient manner. Designed with a unique orange flavor, Keto ACV is a top choice for those looking to lose weight in a safe and effective manner.

Why choose Keto ACV?

There are many reasons why those in need of what they believe to be the best weight loss dietary supplements choose Keto ACV because of its ability to help with weight loss, in addition to providing a wealth of benefits to multiple other aspects of one’s health.
Keto ACV possesses a number of keto-centric benefits which, when combined with the long-studied advantages of apple cider vinegar, have demonstrated they can complement each other with overall weight loss and health benefits as a result.

Moreover, Keto ACV is science based and also tested recently for safety and efficacy. Keto ACV has natural operative ingredients for reducing weight and thus it is safer to have Keto ACV in order to eliminate such weight without any harm to the liver. Several Keto ACV users have claimed that Keto ACV has helped them in reducing weight, cellular efficacy and also overall body health. Thousands of users who have taken Keto ACV are said to have enough energy and nutrition which stimulates their body with additional benefits. Its proven formula along with its users have succeeded to compact the status of Keto ACV to be more trustworthy.

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Apple Cider Vinegar (ACV) and the Ketogenic diet have gained popularity in recent years for their various health benefits. ACV is known for its ability to aid in weight loss, improve digestion, and boost overall health. The Keto diet, on the other hand, focuses on consuming low-carb, high-fat foods to put the body into a state of ketosis, where it burns fat for energy instead of carbs. Now, Simpli has combined the power of ACV and Keto in their new ACV and Keto gummies, promising to deliver the benefits of both in a convenient and tasty form.

The Power of ACV and Keto Combined

Simpli’s ACV and Keto gummies are designed to provide users with the benefits of both ACV and the Keto diet in one easy-to-use supplement. ACV is known for its ability to support weight loss by helping to curb appetite, improve digestion, and boost metabolism. The Keto diet, on the other hand, can help the body enter a state of ketosis, where it burns fat for fuel instead of carbs, leading to weight loss and increased energy levels.

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By combining ACV and Keto in gummy form, Simpli makes it easy for users to incorporate these two powerful ingredients into their daily routine. These gummies are perfect for those who may not enjoy the taste of ACV or find it difficult to stick to the strict guidelines of the Keto diet. With Simpli’s gummies, you can enjoy the benefits of both without the hassle.

Why Choose Simpli’s ACV and Keto Gummies?

There are several reasons why Simpli’s ACV and Keto gummies stand out from other supplements on the market. For starters, these gummies are made with high-quality ingredients and are free from artificial colors, flavors, and preservatives. Each gummy is packed with a potent blend of ACV and Keto-friendly ingredients to support weight loss, digestion, and overall health.

Additionally, Simpli’s gummies are convenient and easy to take on the go. Simply pop a few gummies in your mouth anytime, anywhere for a quick and tasty way to get your daily dose of ACV and Keto. This makes it easy to stay on track with your health goals, even when you’re busy or traveling.

How to Incorporate ACV and Keto Gummies into Your Routine

To experience the full benefits of Simpli’s ACV and Keto gummies, it’s important to incorporate them into your daily routine consistently. Start by taking the recommended dose of gummies each day, preferably with a meal to help with absorption. You can also combine these gummies with a healthy diet and regular exercise for optimal results.

Remember that supplements are meant to complement a healthy lifestyle, not replace it. While Simpli’s ACV and Keto gummies can support weight loss and overall health, it’s essential to also focus on eating nutritious foods, staying active, and getting enough sleep to achieve your wellness goals. With dedication and the help of Simpli’s gummies, you can take your health to the next level.

Get Started with Simpli’s ACV and Keto Gummies Today

If you’re looking to reap the benefits of ACV and the Keto diet in a convenient and delicious form, Simpli’s ACV and Keto gummies are the perfect solution. With their powerful blend of ingredients and easy-to-use format, these gummies can help you achieve your health and weight loss goals with ease. Say goodbye to the hassle of taking multiple supplements – Simpli has you covered with their all-in-one ACV and Keto gummies.

Don’t wait any longer to start your wellness journey. Try Simpli’s ACV and Keto gummies today and experience the transformative power of ACV and Keto combined in one tasty treat. Your body will thank you for it!

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CardioNerds (Drs. Gurleen Kaur and Richard Ferraro) and episode FIT Lead Dr. Spencer Carter (Cardiology Fellow at UT Southwestern) discuss the clinical implementation of GLP-1 receptor agonists with Dr. Neha Pagidapati (Faculty at Duke University School of Medicine). In this episode of the CardioNerds Cardiovascular Prevention Series, we discuss the clinical implementation of glucagon-like peptide-1 (GLP-1) receptor agonists. We cover the clinical indications, metabolic and cardiovascular benefits, and potential limitations of these emerging and exciting therapies. Show notes were drafted by Dr. Spencer Carter. Audio editing was performed by CardioNerds Academy Intern, student Dr. Pacey Wetstein. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - Clinical Implementation of GLP-1 Receptor Agonists GLP-1 agonists work through a variety of mechanisms to counteract metabolic disease. They increase insulin secretion, inhibit glucagon secretion, slow gastric motility, and increase satiety to limit excess energy intake. Patients with type II diabetes and an elevated risk for atherosclerotic cardiovascular disease should be considered for GLP-1 agonist therapy regardless of hemoglobin A1c. GLP-1 agonists offer significant ASCVD risk reduction even in the absence of diabetes. Newer data suggest a significant reduction in cardiovascular events with GLP-1 agonist therapy in patients who are overweight or obese and have a prior history of heart disease. GLP-1 agonists should generally be avoided in patients with a history of medullary thyroid cancer or MEN2. As these medications slow gastric emptying, relative contraindications include history of recurrent pancreatitis and gastroparesis. GLP-1 agonists should be initially prescribed at the lowest dose and slowly uptitrated to avoid gastrointestinal side effects. Show notes - Clinical Implementation of GLP-1 Receptor Agonists What were the groundbreaking findings of the STEP1 and SURMOUNT-1 trials and how these impact cardiovascular wellness? The STEP1 and SURMOUNT trials demonstrated sustained clinically relevant reduction in body weight with semaglutide and tripeptide, respectively, in patients with overweight and obesity. As obesity is an important risk factor for the development of cardiovascular disease, weight reduction meaningfully contributes to cardiovascular wellness. What were the findings of the LEADER trial and their implications for patients with type II diabetes and high cardiovascular risk? The LEADER trial demonstrated a significant reduction in the rate of cardiovascular death, nonfatal MI, or nonfatal stroke in patients with type II diabetes treated with liraglutide. GLP-1 receptor agonist therapy should be considered in all patients with type II diabetes and elevated ASCVD risk regardless of A1c or current hyperglycemic therapy. What are current indications for GLP1 agonists in the context of cardiometabolic disease. GLP-1 receptor agonists should be considered in patients with type II diabetes and high ASCVD risk OR patients without diabetes who are overweight/obese and have a history of cardiovascular disease. What are important side effects or contraindications to GLP1 agents when used for cardiovascular risk reduction and wellness? GLP-1 receptor agonists should be avoided in patients with a history of medullary thyroid cancer or MEN2. Relative contraindications include recurrent pancreatitis, gastroparesis,

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