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Week # 1 of my self made "May Challenge" is compete and this video details you the week that was... My other channel (with my wife): https://www.youtube.com/@UCCitGTkr6mecLQGlR0tiw8w Our video of going to the Thunder playoff game: https://www.youtube.com/watch?v=v1WJj7EzVIA ---------------------- FOLLOW ME: MapMyWalk: [email protected] Instagram: 2BeFatNoMore Instagram: FatDudeTravels MyFitnessPal: Eat2LiveInOKC ______________________ If you like content on weight loss and Mounjaro, here are some other great channels to follow. @JessInProgress @DAVIDKNAPP @bjdavis @Robert_Armstrong73 _______________________ I am paying full price, out of pocket, for Mounjaro. If you would like to help me continue my journey: Venmo - https://www.venmo.com/u/KEDOGN PayPal - [email protected] Cash App - $Kedogn Any and all donations are very appreciated. _______________________ This is my story... I have struggled with weight issues for most of my life. I'd lose some, then gain it and more back every time. I have tried it all: fasting, Weight Watchers, NutriSystem, Herbalife, Slimfast, Adkins, South Beach... you name a fad diet in the past 30 years and I have probably tried it and FAILED! In late December 2021 my wife and I moved to Oklahoma City for work. I looked at this as a 'fresh new start' and I decided that I was going to start a new diet/lifestyle just after the first of the year and so on January 10, 2022, I made the change I needed to and that lasted about a month. I struggled HARD to lose weight. In April of that year I hurt my right knee really bad and had to see a specialist about that. He gave me this look after checking out my knee, and then he looked away towards the wall. He did this a couple times until *I* finally said to him, "Doc are you telling me I need to lose weight?" and he replied something fancy that essentially meant "YES!!". That started me right there on a journey. I **HAD** to lose weight. He was the FIRST ever doc to tell me that, so this would be my motivation... however, a stop by Taco Bell on the way home first was needed since I would be 'going without'. Over the next 4 months I lost and maintained a loss of just 35lbs when I finally set up an appointment with my new Primary Care Physician. I dreaded that appointment as I just knew that she would want to talk about weight and sure enough, about 15 minutes into it she asked me about my weight and if I was interested in losing it. I told her "it's not like I enjoy having it, Doc". She then mentioned Mounjaro to me and I fought her on it immediately. I told her I didn't want to inject into my body something that wasn't meant for it, being that Mounjaro was a medicine for those with Type 2 Diabetes, and I didn't have that. She understood and eventually talked me into trying it. I gave in, reluctantly, and I agreed to 3 months. I told her that if it didn't work in 3 months, I don't want to hear anything else from her again about my weight. That I would give it my best for those 3 months and if it fails, it fails and nothing else can be said. I took my first Mounjaro shot around 9:15am on September 2, 2022 and I weighed 560lbs at that time. Videos on this channel detail my journey from then until now as I have lost over 170lbs since that first shot, even though I have not been able to take the medication as prescribed for various reasons, one being cost. This medicine really is life changing and these videos are the story of how Mounjaro changed my life for the better....

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GLP-1 (Glucagon-Like Peptide-1) inhibitors, more accurately known as GLP-1 receptor agonists, are a class of medications primarily used to treat type 2 diabetes and obesity. Here's a comprehensive look at what they are, how they work, their benefits, and considerations: How They Work: Mimicking GLP-1: GLP-1 receptor agonists mimic the function of the GLP-1 hormone, which is naturally released in the gut in response to food intake. They stimulate insulin secretion from the pancreas when blood glucose levels are high, suppress glucagon release (which would normally increase blood glucose), slow gastric emptying, and increase satiety signals to the brain. Mechanisms: Insulin Release: They help the body release insulin more effectively in response to meals. Glucagon Inhibition: They reduce the amount of glucagon, which helps lower blood sugar. Gastric Emptying: By slowing how quickly food leaves the stomach, they control post-meal blood sugar spikes. Appetite Suppression: They signal to the brain to reduce food intake, aiding in weight management. Benefits: Blood Sugar Control: Effective in lowering HbA1c levels, managing blood sugar in type 2 diabetes. Weight Loss: They have been shown to reduce appetite and body weight, making them useful for obesity management. Cardiovascular and Renal Benefits: Some GLP-1 receptor agonists have demonstrated benefits in reducing cardiovascular risks and improving renal outcomes in diabetic patients. Common Medications: Semaglutide (Ozempic for diabetes, Wegovy for weight loss) Liraglutide (Victoza for diabetes, Saxenda for weight loss) Dulaglutide (Trulicity) Exenatide (Byetta, Bydureon) Tirzepatide (Mounjaro, Zepbound) - a dual agonist that also targets GIP receptor. Side Effects: Gastrointestinal Issues: Nausea, vomiting, diarrhea, and constipation are common, especially when starting treatment. Ozempic Face: Rapid weight loss can lead to sagging skin on the face. Other Side Effects: Less common but more serious side effects include pancreatitis or potential thyroid tumors. Considerations: Administration: Most are injectable, though there's an oral semaglutide option. Cost: These medications can be expensive, potentially limiting access. Off-label Use: There's growing off-label use for weight loss, which brings up debates on ethics, safety, and long-term effects. Insurance and Coverage: Coverage can be variable, with some insurance plans not covering these drugs for weight loss unless certain criteria are met. Long-term Effects: While effective, the long-term effects are still under study, especially with the newer drugs and higher doses used for weight loss. Current Developments: Research: There's ongoing research into their use for other conditions like non-alcoholic fatty liver disease and polycystic ovary syndrome. Market Impact: The popularity of these drugs has significantly influenced the pharmaceutical market, with companies like Novo Nordisk and Eli Lilly seeing substantial growth due to these medications. In summary, GLP-1 receptor agonists represent a significant advancement in managing type 2 diabetes and obesity, offering multiple health benefits alongside some considerations regarding side effects, costs, and ethical use.

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