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Dr Tamaan K. Osbourne-Roberts reviews the list of patients who probably should not be taking GLP-1 receptor agonists. https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?src=soc_yt -- TRANSCRIPT -- Hi. I'm Tamaan K. Osbourne-Roberts, family medicine physician and lifestyle medicine physician, here to discuss GLP-1 receptor agonist (RA) contraindications — the skinny on when not to prescribe. It can be hard not to think of GLP-1 RAs like Ozempic and Mounjaro as silver bullets, long-awaited miracle drugs that we should probably be putting in the water. And it's true they have the potential to help a lot of people. However, there are definitely groups of patients who should not take these drugs or should take them with caution. They include the following: Patients with a family history of certain cancers. Given that GLP-1 RAs can increase the risk for thyroid cancer, patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 should not take these drugs. Gut motility issues. Since one of the primary mechanisms of action for these drugs is to slow down the gut, patients with gastroparesis — diabetic or otherwise — or other gut motility issues should avoid these drugs. Patients with inflammatory bowel disease also should not use GLP-1 RAs. Pancreatitis. These medications can increase the risk for serious pancreatitis on their own, so use in patients who have had pancreatitis already is not recommended. Renal impairment. An eGFR [estimated glomerular filtrationrate] below threshold, typically around 30 mL/min/1.73 m2, excludes GLP-1 RAs for some patients. Be certain to check the threshold for individual medications before prescribing. And finally, pregnancy. These drugs generally should not be used in pregnancy, and people of childbearing age with the ability to become pregnant should use contraception while taking these medications. GLP-1 RAs are great medications and have the potential to revolutionize obesity medicine, but like all drugs, it's important to use them safely. Knowing when not to prescribe them is an important step in ensuring patient safety and will help ensure they are available for those who need them. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?src=soc_yt

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🌟 GLP Drug Updates: Exploring Your Options! 🌟 In this video, we dive into the latest updates on GLP-1 drugs and the alternatives that exist for those seeking better health outcomes. 🩺✨ With the growing interest in these innovative treatments for weight management and metabolic health, it's essential to stay informed about your options. We'll break down what GLP-1 drugs are, how they work, and the impact they can have on your overall well-being. 💊🌿 Whether you're curious about their benefits, availability, or looking for alternative approaches, we've got you covered! Join us as we explore the science, the options, and the steps you can take to make informed health decisions in 2025 and beyond. 🚀💡 Empower yourself with the knowledge you need to make the best choices for your journey to wellness. 👉 Don't forget to like, share, and subscribe for more health-focused content from Healthy by George! 💙 MC shares an update on the GLP/GIP drugs on the Horizon. There is more to learn about these drugs as we see how they can help with the brain/gut connection. Eli Lily has a new three-agonist (retatrutide) in a phase 3 research development showing an even higher percentage of weight loss (22%+) in comparison to the two drugs on the market—tripeptide (18%) and semaglutide (14%). Plus, more is happening in the field that encourages many clinicians to understand that we still don't know why the issue of being overweight and obese is at such an elevated rate. We must continue to advocate for more knowledge and more access so that individuals can have prevention before they are diagnosed with an illness related to being overweight. More needs to be understood about our environment and food sources and how they may contribute to the weight epidemic in our society. Thankfully, medicare is reviewing the addition of these medications for coverage under Medicare and Medicaid. This will give access to more than 3 million individuals who struggle with being overweight and obese. MC shares that she has struggled all her life and that even when complying with lifestyle modifications, the ability to lose weight has not been entirely successful. Now, with the addition of tirzepatide, she has finally found a success she hasn't had in 40 years. Modifying her weight is going to make it easier on her joints and reduce the risk of cancer, heart disease, and sleep apnea. Everyone deserves access to medicines that help prevent developing a chronic illness that prevents us from living a thriving, fulfilling life. Be well, my friends. We have this one precious life; let's live it intentionally. 🌿💚 📌 Disclaimer: The views shared here are solely for education and entertainment. They are not endorsed by my employer or any affiliated companies. This content reflects personal perspectives, and I encourage everyone to consult with healthcare professionals for medical advice. =================================== Watch my More videos 🔰 Catalina Snack Mix Keto Review: Must-Watch! 🎬 https://www.youtube.com/watch?v=mziLKhfubKU 🔰 Boost Your Mood with Essential Oils 🎬 https://www.youtube.com/watch?v=bjTgip4tO5c 🔰 Why choose Organic Foods - Pesticides are related to Cancer 🎬 https://www.youtube.com/watch?v=QH_tcFzXAdQ ============================ ⏰ Video Duration: 00:00:40 https://www.youtube.com/shorts/YabPtytayUc ========================== Follow us on Social Media: Youtube : https://www.youtube.com/@healthybygeorge3425/videos 🔥INSTAGRAM: https://www.instagram.com/healthybygeorge6/ 💎WEBSITE: https://www.marycatherinegeorge.com/ 🔮FACEBOOK: https://www.facebook.com/profile.php?id=100071895693054 📧 For Business Inquiries 📧 Mail: [email protected] ⚠️ hashtags⚠️ #glp1updates #drugoptions #healthnews #weightmanagement #metabolichealth #wellnessjourney #healthylifestyle #diabetesawareness #medicalinnovation #healthtips #healthchoices #betterliving #weightlosstips #wellnessupdates #healthsolutions #metabolismboost #glp1alternatives #personalhealth #wellbeingmatters #nutritiontips #lifelonghealth #healthjourney #balancedliving #weightlossjourney #medicalbreakthroughs #wellnessgoals #healthychoices #fitlife #modernmedicine #wellnessmatters

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Lizzo's Truth: The Real Weight Loss Journey (No Ozempic, Just Hard Work!) Discover the inspiring health journey of Lizzo, the global icon celebrated for her powerful voice and unwavering body positivity. In this video, we dive deep into Lizzo's transformation, debunking Ozempic rumors and shining a spotlight on her real-world strategies—dedicated meal planning, a balanced fitness routine, and holistic self-care practices. Explore her daily diet, from protein-packed breakfasts to healthy dinners, plus her favorite activities like pickleball, hiking, and dancing. Lizzo’s story is about more than just weight loss—it's about self-love, empowerment, and sustainable wellness. Share your thoughts and experiences in the comments, and don’t forget to like and share this video with others on their health journey! #Lizzo #HealthJourney #BodyPositivity #Wellness #Transformation #Buzzfeed

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