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Professor Barry Borlaug presents the SUMMIT trial on the use of the GIP / GLP-1 receptor dual agonist in patients with obesity-associated Heart-Failure with Preserved Ejection Fraction, which has been published in New Engl J Med 2024 and elected the most important study in cardiology and lipidology 2024 by MARKUS at HOMe. Dr. Borlaug is Professor of Medicine and Director, Circulatory Failure Research, Division of Cardiovascular Diseases, and Chair for Research, Division of Circulatory Failure, Department of Cardiovascular Medicine at the Mayo Clinic, Rochester, Minnesota. He is a global leader in studies on mechanisms, diagnosis and treatment of heart failure, particularly heart failure with preserved ejection fraction (HFPEF). The interview was recorded on January 16th, 2025. Moderators: Prof. Dr. Dr. Stephan Schirmer (Kaiserslautern, Germany), Prof. Dr. Florian Custodis (Saarbrücken, Germany) and Prof. Dr. Gunnar Heine (Frankfurt, Germany). Articles discussed: GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders. Leggio L, Hendershot CS, Farokhnia M, Fink-Jensen A, Klausen MK, Schacht JP, Simmons WK. Nat Med 2023 doi: 10.1038/s41591-023-02634-8 Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. Kramer CM, Borlaug BA, Zile M MR, Ruff D, DiMaria JM, Menon V, Ou Y, Zarante AM, Hurt KC, Murakami M, Packer M; SUMMIT Trial Study Group. J Am Coll Cardiol 2024 doi: 10.1016/j.jacc.2024.11.001 Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA; SUMMIT Trial Study Group. N Engl J Med 2024 doi: 10.1056/NEJMoa2410027 Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial. Borlaug BA, Zile MR, Kramer CM, Baum SJ, Hurt K, Litwin SE, Murakami M, Ou Y, Upadhyay N, Packer M. Nat Med 2024 doi: 10.1038/s41591-024-03374-z Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction. Obokata M, Reddy YNV, Pislaru SV, Melenovsky V, Borlaug BA. Circulation 2017 doi: 10.1161/CIRCULATIONAHA.116.026807 An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score. Reddy YNV, Carter RE, Sundaram V, Kaye DM, Handoko ML, Tedford RJ, Andersen MJ, Sharma K, Obokata M, Verbrugge FH, Borlaug BA. Nat Med 2024 doi: 10.1038/s41591-024-03140-1 A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. Circulation 2018 doi: 10.1161/CIRCULATIONAHA.118.034646 How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Pieske B, Tschöpe C, de Boer RA, Fraser AG, Anker SD, Donal E, Edelmann F, Fu M, Guazzi M, Lam CSP, Lancellotti P, Melenovsky V, Morris DA, Nagel E, Pieske-Kraigher E, Ponikowski P, Solomon SD, Vasan RS, Rutten FH, Voors AA, Ruschitzka F, Paulus WJ, Seferovic P, Filippatos G. Eur J Heart Fail 2020 doi: 10.1002/ejhf.1741 Dapagliflozin Enhances Arterial and Venous Compliance During Exercise in Heart Failure With Preserved Ejection Fraction: Insights From the CAMEO-DAPA Trial. Tada A, Burkhoff D, Naser JA, Harada T, Pourmussa B, Reddy YNV, Jensen MD, Carter RE, Demmer RT, Testani JM, Chirinos JA, Borlaug BA. Circulation 2024 doi: 10.1161/CIRCULATIONAHA.124.068788 Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial. Borlaug BA, Reddy YNV, Braun A, Sorimachi H, Omar M, Popovic D, Alogna A, Jensen MD, Carter R Circulation 2023 doi: 10.1161/CIRCULATIONAHA.123.065134
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I noticed a product named Nucentix Keto GMY Gummies with fake reviews and a scam surrounding the subject, possibly including mentions of a TV show, Martha Stewart, Lainey Wilson, Whoopi Goldberg, Dolly Parton, and so many other celebrities who all have nothing to do with it. Nucentix Keto GMY Gummies appears to be a brand new product, as are the fake reviews and scam that surround it. Here's some helpful data on this subject:https://theehealthtool.com/nucentix-keto-gmy-gummies I first noticed this scam going around online in search results and then saw the Nucentix Keto GMY Gummies scam and fake reviews. The scam for Nucentix Keto GMY Gummies as well as the fake reviews will likely lead you to a product purchase page that will ask for your credit card number. Making a purchase of these products through scam websites will charge your credit card hundreds of dollars a month. The purchases from scam websites are subscriptions for monthly recurring charges. These charges might average around $2,000-$3,000 a year. In other words, you do not want to get involved in this. Here's data from the FTC: https://consumer.ftc.gov/consumer-ale.... I've been covering keto gummies scams for quite a while. I'm a reporter by day on another website. This is my personal YouTube channel where I make videos about scams and other subjects on nights and weekends. The Nucentix Keto GMY Gummies pages I show in this video are simply the latest scams that scammers and affiliate marketers are using in order to try to obtain lots of money from potential victims who might not do proper research and to figuring out whether or not something is a scam. I found some helpful data from the BBB: https://www.facebook.com/Keto.GMY.Gummies.Official/ My advice if you purchased Nucentix Keto GMY Gummies from a scam website after seeing fake reviews, that is, if calling a customer service and support number did not work, is to call your credit card company and alert them of the fact that you have been scammed. Let them know you would like to obtain a refund. Please like my video with the thumbs up button, as that'll tell Google and YouTube my video has credibility. That might help my video rise in Google search results and help others not get scammed. Also, please tap the thanks button, which is the heart-shaped symbol to the right of the like button. That would mean a lot to me. Transcript
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LIKE, SUBSCRIBE AND ASK ME QUESTIONS! Instagram @FATANDFITNESS000 *Sorry about the poor lighting
Gin Blossoms Hey Jealousy Official Music Video
My Friends Channel - http://www.youtube.com/user/ASaltyChip Мои дорогие, перемотайте видео вперед до 17:10 для объяснения тренировки на Русском. Меняйте качество на HD в настройках :). Оставляйте все вопросы в комментариях, Я всегда рада ответить на любой вопрос. Дополнительное объяснение тренировки в блоге.
Кардио Вместе Со Мной - ( Real Time Cardio ) - http://www.youtube.com/watch?v=QpyeTMJI3Dk&list=PL9366F25A7921798C&index=3&feature=plcp
Жизнь в Америке. Моя История (запрос) - http://www.youtube.com/watch?v=sNHoYZNPo9U
Challenge Для Осанки ( Good Posture Challenge ) - http://www.lovingfit.com/exercises-workouts/good-posture-and-core-challenge/
Challenge Для Ягодиц ( Round Booty Challenge ) - http://www.lovingfit.com/exercises-workouts/round-and-firm-booty-in-a-month-challenge/
Как Убрать Жир С Боков И Проблемных Мест - http://www.youtube.com/watch?v=GWJJXQgKlrA
Как Накачать Пресс Правильно - http://www.youtube.com/watch?v=LItqv4iSYcM
Тренировка На Грудь ( Подтягиваем ) - http://www.youtube.com/watch?v=adDgKoYqnhA
Целлюлит. Как избавиться от целлюлита - http://www.youtube.com/watch?v=htHOSK-PuLE
Уход за кожей лица ( My Skin Care Routine ) http://www.youtube.com/watch?v=qTlfq0u5LlE
Худеем Без Диет. Мое Питание - My Diet Regimen - http://www.youtube.com/watch?v=_jBzmkQ5Rws
Creating Your Workout Plan ( Как составлять тренировки ) - http://www.lovingfit.com/fitness/creating-your-workout-plan/
Push-Up Program ( Программа Для Отжиманий ) - http://www.lovingfit.com/fitness/improve-your-push-ups/
How To Train For Best Results ( Как Правильно Тренироваться ) - http://www.lovingfit.com/fitness/how-to-train-for-best-results/
Продукты Которые Помогают Балансировать Гормоны ( Hormone Balancing Foods ) - http://www.lovingfit.com/nutrition/hormone-balancing-foods/
Healthy Food Guide and Menu Sample ( Примерное меню и Полезные рецепты ) - http://www.lovingfit.com/nutrition/healthy-food-guide-and-menu-sample/
Full Length Warm-Up ( Разминка ) - http://www.lovingfit.com/exercises-workouts/warm-up-cool-downs/
Full Body Stretching ( Раcтяжка ) - http://www.lovingfit.com/exercises-workouts/total-body-stretching-routine/
Plank Variations ( Варианты Планок ) - http://www.youtube.com/watch?v=6OJt7HyQPEI
How to make a VersaFit Sand Bag ( Как Сделать Сумку С Весом )- http://www.lovingfit.com/fitness/fitness-equipment-on-a-budget/
All The Workouts ( Все Тренировки По Разделам )
Lower Body Routines ( Тренировки На Нижнюю Часть Тела ) -
http://www.lovingfit.com/exercises-workouts/workout-routines/lower-body-workout-routines/
Upper Body Routines ( Тренировки На Верхнюю Часть Тела ) -
http://www.lovingfit.com/exercises-workouts/workout-routines/upper-body-workout-routines/
Abs ( Тренировки На Пресс ) - http://www.lovingfit.com/exercises-workouts/workout-routines/just-abs/
Full Body Workouts ( Тренировки На Всё Тело ) -
http://www.lovingfit.com/exercises-workouts/workout-routines/full-body-workouts/
Facebook
https://www.facebook.com/LovingFitwithTati
VKontakte.ru
http://vkontakte.ru/id11240195
Twitter
http://twitter.com/#!/LovingFit
Music provided by Royalty Free Site - http://incompetech.com/m/c/royalty-free/index.html
Track used in the video : Electro Sketch
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Detailed Recipe & Ingredients Macros (Approx per wrap + dip) Protein: 35-38g Calories: ~380-400 kcal Fats: 12-14g Carbs: 25-30g Protein Wraps (Makes 6) 2 bowls yellow moong dal (soaked for 3-4 hours) 10-12 garlic cloves 4-5 green chillies 1 tsp cumin seeds (jeera) Salt to taste Method ~Blend all ingredients with a little water into a smooth batter. ~Spread like a chilla on a non-stick pan and cook both sides. Set aside. Filling per Wrap 100g homemade low-fat paneer 1 tsp peri peri/mexican spice mix Salt to taste Sliced onion, capsicum, carrot 1 tbsp green chutney (refer to YouTube) Method ~Marinate paneer in spice mix and toast lightly on a pan. ~On the wrap, spread chutney, layer with paneer, veggies, and roll tight. Cut in half. Protein Yogurt Dip (per serving) 1 small bowl protein yogurt (25g protein) 1 tbsp grated beetroot Black salt & chaat masala (a pinch each) Pomegranate arils on top Serve hot, Enjoy! :) #proteinwraps #weightlossrecipes #healthyrecipes #highproteinmeal #moongdalwrap #paneerrecipes #indianweightloss #homemadewraps #lowcaloriemeals #fatlossrecipes #vegetarianprotein #greenchutneywrap #easyindianrecipes #musclebuildingfood #cleaneating #healthyeating #fitmeals #lunchboxideas #weightlossfood #mealprepideas #highproteinvegetarian #fitfoodie #indianfitnessmeals #quickmeals #maidafreewraps #healthywraps #plantprotein #gymdietmeal #indianmealideas #wrapmeal #homemadelunchbox #chillarecipe #noboringmeals #lowfatrecipes #postworkoutmeal #highproteinwrap #healthylifestyle #weightlossideas #proteinpackedmeal #paneerlover #fitnessmealsindia #moongdalrecipe #gutfriendlymeal #healthyvegetarian #noattarecipes #quickweightlossmeal #easyproteinwrap #proteinindianmeal #musclegainrecipes #vegetarianweightloss high protein veg wraps, protein wrap recipe, moong dal wrap, weight loss wrap recipe, high protein vegetarian meal, paneer wrap recipe, fat loss meal idea, low calorie vegetarian wrap, healthy Indian wrap, moong dal chilla wrap, post workout veg meal, homemade protein wraps, healthy lunch wraps, 38g protein meal, healthy wraps for lunch, protein meal under 400 calories, vegetarian wrap Indian style, low carb Indian wrap, easy weight loss dinner, high protein chilla wrap, Indian gym food, vegetarian muscle gain meal, weight loss lunch ideas Indian, healthy paneer recipe, quick healthy meal Indian, vegetarian macro meal, green chutney wrap, healthy meal prep Indian, no maida recipe Indian, clean eating vegetarian recipe, Indian protein wrap recipe, easy dinner for weight loss, Indian protein packed wrap, gluten free Indian wrap, wrap without maida, healthy moong dal recipe, no wheat protein wrap, 100g paneer recipe, vegetarian high protein lunch, vegetarian post workout meal, moong dal wrap recipe, easy healthy Indian meal, fat loss lunch Indian, muscle building Indian food, healthy tiffin recipe, meal prep for fat loss, Indian recipe for weight loss, quick veg wrap, high protein Indian recipe, healthy weight loss Indian meal, easy protein wrap for gym, low calorie paneer wrap, high protein Indian diet, vegetarian fitness meal, Indian healthy wrap meal, high protein wrap meal idea, easy Indian recipe for gym diet, fat loss vegetarian wrap, healthy food Indian vegetarian, clean Indian meal, Indian chilla wrap recipe, quick vegetarian dinner recipe, Indian diet recipe for muscle, 38 gram protein meal, Indian high protein wraps, weight loss friendly wrap, meal prep vegetarian Indian, veg wraps for fat loss