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GLP-1 agonists are not only for weight loss but also for patients with diabetes. Anne Peters, MD, discusses the importance of monitoring dosing between insulin and GLP-1 agonists. https://www.medscape.com/viewarticle/997976?src=soc_yt -- TRANSCRIPT -- We've all been hearing about the weight loss benefits of glucagon-like peptide 1 (GLP-1) receptor agonists, but it's important to remember that they are also diabetes medications. If you have a patient who's on an insulin secretagogue and/or insulin, it's important to remember that you need to adjust those medications to avoid hypoglycemia as you start and uptitrate the GLP-1 receptor agonist. This isn't really cookbook, in the sense that you have to think about each patient, but I'll tell you what I do. First, I try to have most of my patients on continuous glucose monitors (CGM) because if they're on CGM, I can look at the trends to see what's happening as I'm adding a GLP-1 receptor agonist. If they're not on CGM, it's helpful if they test a fasting glucose level and perhaps a postprandial, though it's harder to get people to do, because you want to know whether to reduce the basal insulin or the prandial insulin. Regardless of testing, you need to review with the patient the signs and symptoms of hypoglycemia and how to treat it if it occurs. In a patient on insulin, you may want to make sure they have glucagon at home because there have been episodes of severe hypoglycemia when a GLP-1 receptor agonist was added to insulin. As a rule of thumb, I start by looking at the A1c. If the A1c is above 8%, I'm probably not going to do much reduction in the insulin secretagogue or the insulin right off the bat. I'll watch the patient as they begin to respond to the GLP-1 receptor agonist and then start tapering down the insulin if their glucose levels fall. I often reduce the prandial insulin levels first because you're going to start seeing the patient eating less and be at increased risk for hypoglycemia between meals. If I start seeing the fasting glucose fall, then I'll start reducing the basal insulin. Usually, I reduce the doses by 10%-20%. As I said, in somebody who starts out with a higher A1c, I don't right off the bat reduce the insulin. I watch what happens as the dose is increased. As the dose is increased in someone who's on an oral insulin secretagogue, I'll tend to cut that dose in half as I see glucose levels coming down. On the other hand, if someone's starting A1c is below 8%, I might start by reducing their prandial insulin by 50% and maybe their basal insulin by 10%-20%, depending on their glucose levels. I think patients who are closer to target on insulin and/or a sulfonylurea agent are going to be at increased risk for going low. Ideally, one can taper the patient off their insulin — and if not entirely off their insulin, off their prandial insulin — because it's much easier to give basal insulin and a once-weekly GLP-1 receptor agonist than to be on a multiple daily insulin regimen. Potentially, you'll be able to taper your patient off their insulin secretagogue as well. The important thing to remember is that there's more than one moving target. You're uptitrating the GLP-1 receptor agonist or the GIP/GLP-1 receptor agonist and you're downtitrating the insulin secretagogue and/or the insulin. You want to downtitrate in gradual steps to keep ahead of any risk for hypoglycemia. Usually, that is done in slow steps, say, 10%-20% at a time. It also means that you pay attention to your patients and that you may need to follow them every week or two, particularly if their A1c starts out below 8%, where they're likely to be at more risk for hypoglycemia. If you pay attention to this process, you should be able to get your patient to a better point, hopefully on less medication that can cause hypoglycemia, and onto a medication that not only improves glucose but also helps with weight reduction, improves cardiovascular outcomes, and may have a renal benefit. Thank you. https://www.medscape.com/viewarticle/997976?src=soc_yt
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PART 2 - HOW TO DRINK WATER TO LOSE WEIGHT Isa isahin po natin ang inyong mga request and questions. :) Hello Madla. Welcome back to my youtube channel. 😊 For this video, i-share ko sainyo ang effectivity ng Water Therapy for weightloss. This is based on Japanese Water Therapy. Para sa video ng aking "PAANO PUMAYAT | 4 EASY AND EFFECTIVE TIPS TO LOSE WEIGHT FAST", please click the link below: https://youtu.be/GaS0KW5WCWY Sit back, relax and enjoy watching my video. Subscribe, Like, Comment and Share na din po. 😊 Godbless and Stay healthy! :) Sana po makatulong ito sa inyo! ❤ Thank you Madla! #Watertherapyforweightloss #Paanopumayat #Paanopumayatngmabilis #Diettips #Weightlossjourney #Paanopumayatgamitangtubig #Watertherapy #Japanesewatertherapy Related searches: paano ako pumayat viy, paano ako pumayat ng mabilis, paano ako pumayat 2020, paano ako pumayat apple cider, paano ako pumayat gamit ang tubig, paano nga ba ako pumayat, paano ako pumayat viy cortez, paano ako pumayat low carb, paano ako pumayat with exercise, paano ako pumayat intermittent fasting, paano ako pumayat journey, paano ako pumayat lcif, kath melendez paano ako pumayat, paano ako pumayat no rice, paano ako pumayat pinoy md, paano ako pumayat philippines, paano ako pumayat sa tubig, paano ako pumayat teenager, my weightloss journey, my weight loss journey female, my weight loss journey intermittent fasting, my weightloss journey as a teenager, my weight loss journey at home, my weight loss journey before and after, my weight loss journey before and after teenager, my weight loss journey before and after pictures, my weight loss journey blog, my weightloss journey chloe ting, my low carb weight loss journey, my weight loss journey day 1, my weightloss journey documentary, my extreme weight loss journey, my fast weight loss journey, my fitness journey weight loss transformation, follow my weight loss journey, my weightloss journey girl, my healthy weight loss journey, my weight loss journey philippines, my real weight loss journey, my weightloss journey story, paano pumayat gamit ang tubig, paano pumayat ang tiyan, paano ba pumayat, paano ba pumayat ng mabilis, paano pumayat apple cider vinegar, paano ako pumayat apple cider, paano pumayat diet meal plan, paano pumayat diet, paano pumayat work out, paano pumayat in just 2 weeks, sweet potatoes diet to lose weight, sweet potatoes keto diet, sweet potatoes for diet, sweet potatoes on keto diet, paano pumayat ang binti at hita, paano pumayat charm, paano pumayat coach dave, paano ako pumayat apple cider, paano ako pumayat low carb, paano pumayat doc adam, paano pumayat doc willie, paano pumayat doc willie ong, paano pumayat dr willie ong, paano pumayat si emma, paano pumayat gamit ang calamansi, paano pumayat gamit ang chia seeds, paano pumayat in 1 day, paano pumayat in 1 week no exercise, paano pumayat in 5 days, paano pumayat jhocel, paano pumayat kahit nasa bahay lang, paano pumayat kath melendez, paano pumayat lalaki, paano pumayat luya, paano pumayat lemon, paano pumayat low budget, paano pumayat male, paano pumayat ng mabilis at walang exercise, tips kung paano pumayat ng mabilis, paano pumayat ng 1 week, paano pumayat no exercise, paano pumayat na walang exercise, paano pumayat ng isang linggo, paano pumayat ng walang diet, paano pumayat ng 1 month, paano pumayat oatmeal, paano pumayat in one month, paano pumayat doc ong, paano pumayat work out, paano pumayat ng one week, paano pumayat pinoy md, paano pumayat pagkain, paano pumayat pag may pcos, paano pumayat part 1, paano pumayat ang binti at hita, paano pumayat charm, paano pumayat coach dave, paano ako pumayat apple cider, paano pumayat sa chia seeds, paano ako pumayat low carb, paano pumayat doc adam, paano pumayat doc willie, paano pumayat doc willie ong, paano pumayat dr willie ong, paano pumayat in 1 week no exercise, paano pumayat in 5 days, paano pumayat in 2 months, paano pumayat jhocel, paano pumayat kath melendez, paano pumayat lemon, paano pumayat low budget, paano pumayat ng mabilis at walang exercise, tips kung paano pumayat ng mabilis, paano pumayat ng 1 week, paano pumayat no exercise, PAANO AKO PUMAYAT?! (How I Lost 30lbs) + My Weight Loss Journey | Toni Sia
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