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Welcome to The Chemist Couple podcast! With GLP-1 medications like Mounjaro becoming more popular, are we overlooking the risks? From potential nutrient deficiencies to serious health concerns like pancreatitis and diabetic retinopathy, we break it all down. Don't let the hype overshadow the science! ⚠️ ⏱️ Timestamps: * 00:00 - The Rise of GLP-1s: Why Are They So Popular? * 01:56 - Eating Less = Harm? The Hidden Risks * 03:43 - Losing Lean Mass: What You Need to Know * 04:55 - The Risk of Vitamin Deficiencies * 05:58 - Can You Keep the Weight Off? Leptin Explained * 07:51 - Lifestyle Changes: Key to Long-Term Success * 10:18 - The ‘Golden Dose’: A Dangerous Shortcut? * 11:57 - ‘Microdosing’ GLP-1s: Risky & Unlicensed! * 14:31 - Surgery & Aspiration: A New GLP-1 Warning * 18:36 - Just How Powerful Are GLP-1s? * 19:32 - Diabetic Retinopathy: An Overlooked Side Effect * 22:05 - Pancreatitis: A Rare but Serious Risk * 23:55 - Fertility, Pregnancy & Breastfeeding: What’s Safe? * 29:20 - Planning a Pregnancy? Here’s What to Consider * 30:21 - Final Thoughts: Are GLP-1s Worth the Risk? 🔔 Subscribe to The Chemist Couple Podcast: Stay on top of the latest science-based preventative health tips. Hit the like button and tell us: What are your thoughts on GLP-1 medication? 🎙️ Listen to our podcast: Spotify 🎧: The Chemist Couple PodcastApple Podcasts 🍏: The Chemist Couple Podcast 📩 Sign up for our newsletter to learn how we personally apply science to enhance our lifestyle: Join Here 📺 Watch this episode on YouTube: The Chemist Couple Podcast 📚 Studies Referenced in This Episode: * Guyton & Hall Medical Physiology (14th Edition) – General physiology overview * Rang & Dale’s Pharmacology (10th Edition) – General pharmacological overview * Electronic Medicines Compendium (EMC): Mounjaro (tirzepatide) Summary of Product Characteristics – Read Here * Diabetes & Primary Care, Vol 23 No 4 (2021): GLP-1 receptor agonists and diabetic retinopathy – Read Here ⚠️ Disclaimer: This podcast is for informational purposes only and should not replace advice from a healthcare professional. If you have any questions, reach out to us. Thanks for watching!

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[ TAKE THE PHYSIQUE QUIZ ] http://Quiz.SeanNal.com [ RECOMMENDED SUPPLEMENTS ] http://www.RealScienceAthletics.com [ CONNECT WITH ME ] https://www.instagram.com/Sean_Nalewanyj https://www.facebook.com/SeanNalewanyj ------------------------------------------------------------------------- Calories In Vs. Calories Out = Outdated Science Or Key Fat Loss Principle? Is “calories in vs. calories out” (CICO) an accurate model for fat loss, or is it "outdated science" like some people try to claim? Do calories matter when it comes to leaning down and burning fat? This is a pretty common fat loss debate you'll see online nowadays... One person will state that in order to lose fat, you need to create a calorie deficit by consuming fewer calories than you burn. Someone else will then argue back that calories "don’t matter" because not all calories are the same. However, the latter statement is fundamentally incorrect right off the bat since a calorie is a constant unit of energy. Just like pounds measure weight or kilometers measure distance, calories measure energy. Therefore a calorie IS a calorie no matter what food it’s contained in. What people usually mean to say here is that your body will process different *foods* differently depending on their nutrient profile and fiber content, which is true. For example, 250 calories worth of chicken and broccoli will provide protein for muscle growth and be more micronutrient-dense, higher in fiber, more satiating and have a higher thermic effect than, say, 250 calories of jelly beans. The calories themselves are the same, but the food they're packaged up in is different. So yes, 2000 calories on paper from one combination of foods will not necessarily produce the same fat burning and muscle building effect as 2000 calories on paper from a different combination. The problem though is that people will then take this information and make a massive leap by saying that since food quality impacts the way calories are handled from different foods, that this then means that "calories don’t matter" and that calories in vs. calories out is somehow irrelevant. However, what many fail to realize is that the way food quality impacts fat loss is still primarily a result of how it influences net energy balance, or calories consumed versus calories burned. For example, eating more protein causes your body to burn more calories through digestion due to it having a higher thermic effect. Eating more fiber causes your body to absorb fewer calories from your protein and fat intake. So, these things are literally affecting the "calories in" and "calories out" portion of the energy balance equation. The bottom line is that body fat is a stored form of energy, and the way you stimulate your body to release that fat is by creating a calorie deficit where the amount of available energy from the foods you consume is less than what your body requires to fuel itself throughout the day. To say that calories don’t matter or that calories in vs. calories out is irrelevant is just flat-out incorrect and is a basic misunderstanding of how the fat burning process actually work. Yes, if your diet is currently very poorly structured (low protein, low fiber, centered around calorie-dense high-fat, high-sugar foods), and you aren’t weight training, fixing those issues by basing your diet around minimally processed whole foods with at least 0.8 grams of protein per pound of body weight daily, more veggies and high-fiber foods along with a good weight training plan - that will help you lose fat in the initial stages probably without needing to track calories at all. However, once you have a decent fat loss diet with a balanced macronutrient breakdown that is centered around minimally processed whole foods, there isn't much else you can do to manipulate "food quality" beyond that point to continue losing fat. At that point it really is just about managing calories in versus calories out on paper. (After all, if you're "eating clean" and your fat loss stalls, what do you do then? Eat cleaner?) This doesn’t necessarily mean you have to track every every single calorie you eat, although most people probably will benefit from tracking at least in the beginning stages. How many calories should you eat to lose fat in a consistent and sustainable way? A good sweet spot to aim for is about 300-500 calories below maintenance per day. To sum up: Both your calorie intake AND the quality of the foods you eat matter for fat loss, overall health, gym performance and muscle growth. However, losing body fat ultimately comes down to creating a consistent calorie deficit when it all comes down to it. That calorie deficit can be partly influenced by your food choices and macronutrient breakdown, but once you have a decent nutrient-rich whole-food diet in place, calories in versus calories out is where your primary focus should be in order to maximize your long-term results.

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🔥 30% to 10% Body Fat – 10 Proven Steps That Actually Work 🔥 Are you ready to transform your body and achieve a lean, shredded physique? In this video, I’ll walk you through the exact 10 steps I used to drop from 30% to 10% body fat naturally — no shortcuts, no gimmicks, just science-backed strategies that work. ✅ What you’ll learn in this video: The best foods for burning fat and fueling your body How to create a sustainable calorie deficit Why protein and fiber are essential for lasting fat loss Powerful resistance training & HIIT workouts that torch fat How to manage stress, sleep better, and stay consistent long-term 💡 Bonus Tip at the End: Learn how to still enjoy a weekly cheat meal without sabotaging your progress! Whether you’re starting your fitness journey or looking to take your fat loss to the next level, this video will give you clear, actionable steps to cut fat while maintaining muscle. 👍 If you're ready to get lean, hit that LIKE button 💬 Share your biggest fat loss challenge in the COMMENTS 🔔 SUBSCRIBE for more tips on fat loss, muscle gain, and total body transformation #fatloss #bodytransformation #shredded #losebodyfat #fitnessmotivation #cuttingtips

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The new GLP1 weight loss drugs are the new trend, but are they safe to take if you're trying to become pregnant? Dr. Linda explores this challenge and recommends that women who desire fertility have frank, honest discussions with their healthcare provider before starting these drugs. #ozempac, #semaglutide #mounjaro #weightloss #pregnancy #pregnancyjourney #IVF #IVFjourney