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gip and glp GIP and GLP are abbreviations for two important hormones involved in the regulation of blood sugar levels and digestion: glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1). GIP (Glucose-Dependent Insulinotropic Peptide): GIP is a hormone secreted by cells in the small intestine in response to the ingestion of carbohydrates, particularly glucose and fat. Its primary role is to stimulate the release of insulin from pancreatic beta cells. GIP is considered an incretin hormone because it enhances the secretion of insulin from the pancreas in a glucose-dependent manner, meaning it is released when blood glucose levels are elevated. GIP also inhibits glucagon secretion from the pancreatic alpha cells and promotes the storage of fat in adipose tissue. GLP-1 (Glucagon-Like Peptide-1): GLP-1 is a hormone secreted by cells in the small intestine, specifically the L cells, in response to the presence of nutrients in the digestive system. GLP-1 has multiple effects on the body. One of its primary roles is to stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner. It also inhibits glucagon release from pancreatic alpha cells, which helps to lower blood glucose levels. GLP-1 slows down the emptying of the stomach, which can contribute to a feeling of fullness and aid in appetite control. Additionally, GLP-1 has been found to promote the growth and proliferation of beta cells in the pancreas. Both GIP and GLP-1 play crucial roles in the regulation of glucose metabolism and the control of blood sugar levels. They are part of the incretin system, which is involved in the fine-tuning of insulin and glucagon secretion based on the nutritional status of the body. These hormones have also gained attention in the management of type 2 diabetes, as medications known as GLP-1 receptor agonists and DPP-4 inhibitors that target these pathways have been developed to help regulate blood sugar levels in individuals with diabetes @umerfarooqbiology7083 #gip #glp1 #obesity #muhammadumerfarooqbiology

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Downsized News: Breakthroughs and Industry Shifts in GLP-1 Treatments In this episode of the Downsized News, Laraine and Christopher Durham deliver the latest updates on GLP-1 medications on Monday, June 2nd, 2025. Key topics include significant data releases by Eli Lilly at the upcoming American Diabetes Association's Scientific Sessions concerning Tirzepatide's effects on kidney function and weight loss compared to Semaglutide. The episode also explores new forms of GLP-1 treatments, such as the Orfroglipron pill and the Retatrutide triple-action hormone, as well as an updated weekly insulin option by Lilly. Additionally, a comprehensive breakdown of a study on high-dose Semaglutide treatments for diabetes and obesity discusses the balance between increased weight loss and rising side effects. The discussion shifts to industry challenges, like Hims Inc.'s layoffs due to FDA crackdowns on compounded GLP-1s, and a new ISSA course designed to help athletic trainers support GLP-1 users. Also covered is the intense industry debate over compounded medications, a major court ruling in India impacting Semaglutide sales, and competitive developments in China's obesity treatment market. The episode concludes with highlights of an innovative partnership between Nxtera Pharma and Eli Lilly aiming at new metabolic treatments. The hosts encourage viewers to stay informed and share personal insights on navigating GLP-1 treatments. DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store Join CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED WEBSITE: https://thedownsized.org/ FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction and Overview 01:04 Eli Lilly's Latest Data and Innovations 05:21 High Dose Semaglutide Study Insights 10:14 Hims Layoffs and FDA Crackdown 11:51 New Training Course for GLP-1 Trainers 13:58 Compounded Medications Debate 17:08 Legal Battles and Market Dynamics in India 20:16 NextEra Pharma and Eli Lilly Partnership 21:52 Upcoming Competition in China's GLP-1 Market 24:25 Conclusion and Final Thoughts

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Keto Blast Max Gummies are packed with powerful ingredients that can help you reach ketosis faster and stay there longer. With a blend of BHB ketones, MCT oil, and other natural ingredients, these gummies are designed to support your body’s natural fat-burning process. By taking Keto Blast Max Gummies regularly, you can increase your energy levels, curb cravings, and support your overall weight loss journey.

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It is not recommended to take Keto Blast Max Gummies if you are pregnant or nursing, as the effects of the ingredients on a developing fetus or infant are not fully understood. It is best to consult with your healthcare provider before taking any new supplement while pregnant or nursing.

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