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Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv Disclaimer:- This video is for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have watched on this channel. Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired, By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are incretin hormones that promote insulin secretion and regulate blood glucose levels. Elevated levels of GLP-1 and GIP consequently results in improved glycemic control.6 In clinical trials, vildagliptin has a relatively low risk of hypoglycemia. Vildagliptin is indicated in the treatment of type II diabetes mellitus in adults. As monotherapy, vildagliptin is indicated in adults inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to contraindications or intolerance. It is also indicated as dual therapy in combination with metformin, a sulphonylurea, or a thiazolidinedione in adults patients with insufficient glycemic control despite maximal tolerated dose of monotherapy. Vildagliptin is indicated in the treatment of type II diabetes mellitus in adults. As monotherapy, vildagliptin is indicated in adults inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to contraindications or intolerance.6 It is also indicated as dual therapy in combination with metformin, a sulphonylurea, or a thiazolidinedione in adults patients with insufficient glycemic control despite maximal tolerated dose of monotherapy. Vildagliptin is also marketed in a combination product with metformin for the treatment of adults with type II diabetes mellitus who inadequately respond to either monotherapy of vildagliptin or metformin. This fixed-dose formulation can be used in combination with a sulphonylurea or insulin (i.e., triple therapy) as an adjunct to diet and exercise in adults who do not achieve adequate glycemic control with monotherapy or dual therapy. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) are incretin hormones that regulate blood glucose levels and maintain glucose homeostasis. It is estimated that the activity of GLP-1 and GIP contribute more than 70% to the insulin response to an oral glucose challenge. They stimulate insulin secretion in a glucose-dependent manner via G-protein-coupled GIP and GLP-1 receptor signalling. In addition to their effects on insulin secretion, GLP-1 is also involved in promoting islet neogenesis and differentiation, as well as attenuating pancreatic beta-cell apoptosis. Incretin hormones also exert extra-pancreatic effects, such as lipogenesis and myocardial function Get in touch with the solution Pharmacy and Pharmacy Dictionary by just clicking the following links- Mobile App - https://play.google.com/store/apps/details?id=co.bolton.nqilv Facebook Group- https://www.facebook.com/groups/solutionpharamcy The main channel for a detailed Syllabus (Solution- Pharmacy) - https://www.youtube.com/c/SOLUTIONpushpendra E-Mail for official and other work - [email protected] #Pharmacydictionarybypushpendrapatel #Pharmacologyclass
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πSave an extra 20% off goli ACV gummies on amazon here: https://geni.us/i4iW πGet My FREE GUIDE, β β RECOMMENDED SUPPLEMENTS β β - https://bit.ly/2yWVkpD β ππππππ ππππβ https://solo.to/sethkardos [π€ Discount codes: Products, Services, Supplements, etc] πΈ Follow Me on INSTAGRAM https://www.instagram.com/sethkardosfit/ πMy favorite pre-workout: https://geni.us/sK9SQdo (only pre w/ paraxanthine on the market) πsubscribe to my other channel: https://www.youtube.com/channel/UCKxWdYU3QMBBmk4OzbM5MjA/ πMy Amazon Store (Products I use): https://geni.us/IAMmn3 Apple Cider Vinegar (ACV) Gummies have gained popularity as a convenient and tasty alternative to traditional liquid ACV. They are marketed for a range of health benefits, including digestion, weight management, and overall well-being. Here's a detailed review: Key Ingredients in ACV Gummies Apple Cider Vinegar: Typically contains 500β1000 mg of ACV per serving. Often includes "the mother," which contains beneficial enzymes, proteins, and bacteria. Added Nutrients (Varies by Brand): B Vitamins: Support energy metabolism and overall health. Pectin: A natural fiber that aids digestion. Superfoods or Herbal Extracts: Such as beetroot, ginger, or pomegranate for added benefits. Sweeteners and Flavorings: Often sweetened with natural sugars or alternatives to mask ACV's tart flavor. Potential Benefits of ACV Gummies Supports Digestive Health: May improve digestion by promoting the growth of healthy gut bacteria. Can help alleviate bloating and indigestion. Aids in Weight Management: Some studies suggest ACV may help reduce appetite and support fat metabolism. Provides a feeling of fullness, which can help control calorie intake. Regulates Blood Sugar Levels: ACV may improve insulin sensitivity and help stabilize blood sugar levels after meals. Boosts Energy: B vitamins and other added nutrients may enhance energy and reduce fatigue. Supports Detoxification: Contains antioxidants that help eliminate toxins and support liver function. Improves Skin Health: Some users report clearer skin, potentially due to detoxifying properties and better digestion. Heart Health: May help lower cholesterol levels and improve overall cardiovascular health. Pros of ACV Gummies Convenient and Palatable: Easy to consume without the harsh taste or acidity of liquid ACV. Portable and mess-free. Gentle on the Stomach: Less likely to cause stomach irritation compared to liquid ACV. Vitamin-Enriched: Many brands include added nutrients, enhancing the overall benefits. Suitable for Most Diets: Often vegan, gluten-free, and free from artificial additives. Cons of ACV Gummies Lower ACV Content: Typically contains less ACV compared to liquid form, which may limit its effectiveness. Added Sugar: Some brands include added sugars, which can reduce their health appeal. Cost: More expensive than liquid ACV. 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