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Wegovy, the blockbuster weight-loss drug, is now available in Singapore more than two years after it was approved by the Health Sciences Authority. Synopsis: Join us every Thursday at 12pm SG/HK as The Straits Times' Natasha Ann Zachariah unpacks the latest current affairs with guests. But its arrival here sparks a deeper conversation about who should take it, how it makes us rethink obesity and weight loss, and whether weight-loss drugs are a magic bullet. Earlier in July, pharmaceutical firm Novo Nordisk, which makes Wegovy, announced in a statement that the injectable drug is now available with prescription from any licensed physician at hospitals and clinics across Singapore. The global hype around Wegovy, which is made for weight loss, stemmed from Ozempic, which was created as an anti-diabetic drug. The latter garnered a lot of attention on social media a few years ago after its users, who weren’t all diabetics, showed off their considerable weight loss. What connects Wegovy and Ozempic – besides both being made by Novo Nordisk – is that they contain the active ingredient semaglutide. Mimicking the natural hormone glucagon-like peptide-1, semaglutide regulates blood sugar levels, curbs the appetite and induces the sensation of fullness. One of the differences? Wegovy has a higher maximum dosage of 2.4mg than Ozempic’s 2mg. While the benefits have been laid out, what should those considering Wegovy look out for? To answer these questions on this episode of The Usual Place, I have: Senior consultant endocrinologist Dr Sue-Anne Toh from Novi Health, a specialist medical clinic and health-tech company. She has more than 20 years of experience in internal medicine, diabetes, and metabolic health. Her patient Farhan Hanis, a 26-year-old university student and a former plus-sized model. He started on Wegovy about two months ago. General practitioner Dr Bosty Chan, who co-founded health telemedicine providers Sire and Dame, which offers weight management as part of its suite of services. This episode was recorded on 24 July, 2025. Highlights (click/tap above): 00:00 Intro 3:03 Dr Toh on whether there is a difference between Wegovy and Ozempic 4:13 Gamechanger to the weight loss market in Singapore? How do these options compare with surgically invasive options? 8:00 Dr Chan: Singaporeans are quite well-researched before they ask about options; more clinical data available these days 11:12 Why Farhan chose this route two months ago; family history concerns and any side effects? 14:20 How Farhan dealt with his weight concerns before 16:15 Dr Toh on understanding biology, why some cannot lose weight easily; how GLP-1 hormones work 18:32 Drugs like Wegovy are not a magic bullet, critical to form the right habits alongside 20:02 What is 'Ozempic face'? 22:00 Farhan on adopting the right habits; what he feels when he tries to eat processed foods now 24:38 Dr Chan on his digital experience in the telemedicine sector so far, the transparency needed to determine genuine consultations 27:00 There is still a secondary 'hybrid' channel for patients to come in, he says, but trust is critical 34:37 More normalised to talk about weight treatment now, patients more open about obesity 39:50 Managing costs of such GLP-1 medication 45:00 Dr Chan on whether weight-loss drugs are supposed to be for the long term 51:05 Dr Toh on understanding metabolic adaptation even in other ways such as intermittent fasting 53:41 Does Singapore have a problem with obesity? 1:00:17 Should Singapore redefine obesity markers for the population? 1:02:39 Farhan on being a plus-sized model and speaking out about definition of body positivity Host: Natasha Ann Zachariah ([email protected]) Read Natasha’s articles: https://str.sg/iSXm Follow Natasha on her IG account and DM her your thoughts on this topic: https://str.sg/8KNT Follow Natasha on LinkedIn: https://str.sg/v6DN Filmed by: Studio+65 ST Podcast producers: Teo Tong Kai & Eden Soh Executive producers: Ernest Luis & Lynda Hong Follow The Usual Place Podcast and get notified for new episode drops every Thursday: Channel: https://str.sg/5nfm Apple Podcasts: https://str.sg/9ijX Spotify: https://str.sg/cd2P YouTube: https://str.sg/theusualplacepodcast Feedback to: [email protected] Follow The Straits Times Podcasts on YouTube: https://str.sg/GFLv Turn on notifications 🔔 to stay updated. -------------------- Discover more ST podcast channels: All-in-one ST Podcasts channel ➤ https://str.sg/wvz7 Get The Straits Times' app, which has a dedicated podcast player section: The App Store ➤ https://str.sg/icyB Google Play ➤ https://str.sg/icyX

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Ozempic has taken the pharmaceutical world by storm. Initially approved as an injection for diabetes and now known by many as THE weight-loss drug, research has shown that such drugs actually could be use to treat more than one condition. Last year, Wegovy - a version of Ozempic approved for weight loss - was shown to reduce the risk of heart attack and stroke, improve cognitive function in people with Alzeheimer's and even showed hints of benefitting fertility. ⁠ ⁠ Why this drug is helping so many conditions is still somewhat of a mystery, but researchers are beginning to unravel the mechanisms underlying its extraordinary abilities. ⁠ ⁠ Learn more ➤ https://www.newscientist.com/article/2456669-why-do-ozempic-and-wegovy-seem-to-treat-everything/ Subscribe ➤ https://bit.ly/NSYTSUBS Get more from New Scientist: Official website: https://bit.ly/NSYTHP Facebook: https://bit.ly/NSYTFB Twitter: https://bit.ly/NSYTTW Instagram: https://bit.ly/NSYTINSTA LinkedIn: https://bit.ly/NSYTLIN About New Scientist: New Scientist was founded in 1956 for “all those interested in scientific discovery and its social consequences”. Today our website, videos, newsletters, app, podcast and print magazine cover the world’s most important, exciting and entertaining science news as well as asking the big-picture questions about life, the universe, and what it means to be human. New Scientist https://www.newscientist.com/