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Episode #149 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community: • I’ve heard you’ve written an amazing book called, “The Cancer Code.” I haven’t read it yet, but wanted to hear your thoughts on broccolini being an anti-cancer food. I understand it contains Sulforaphane, Indole-3-carbinol (I3C), Glucosinolates, Vitamin C, and fiber. Should I concentrate on cruciferous vegetables, like broccolini, or just work on getting a balanced diet? What are your thoughts? [02:14] • I have a little confusion about the difference between taking metformin and injecting insulin. From what I've read in your books it's that insulin is going to make type 2 diabetes worse in the long run. I already know that that’s not the answer to reverse type two diabetes and I’m not taking either one. Like insulin, will metformin also be detrimental to treat T2D or is there a difference between one and the other - and why, please? [05:27] • What do they mean by 'immunoreactive insulin'? [12:06] • Does the liver respond negatively to the ingestion of supplements? In other words, do the supplements cause any changes in my insulin? [14:52] • I started TRE (beginning Jan this year) at about 135 pounds and am now doing 24-hour fasts with OMAD and 2MAD. I have completed a 42-hour fast and will probably try another one this week. I am eating whole foods. Avocados are my miracle!!! I do not snack between meals. My body is still releasing weight with what I am doing now and I feel I have another 5 pounds to go. How will I know when to stop shedding the weight? [18:13] • Can you clarify the role of physical activity and exercise in weight loss? In The Obesity Code, you shared that a number of rigorous clinical trials demonstrate that exercise contributes minimally, if at all, to weight loss. However, zone 2 exercise is promoted for its'fat burnin' benefits. I plan to continue exercising for its health-promoting benefits but I would really like to hear your take on the extent to which it can assist with weight loss, and what exercise types you recommend for weight loss. [21:56] • On non-fasting days, what is Dr. Fung’s chosen style of eating? [29:46] Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs Transcripts of all episodes are available at www.thefastingmethod.com on the Podcast page. Learn More About Our Community: https://www.thefastingmethod.com Join our FREE Facebook Group: https://bit.ly/TFMNetwork Watch Us On YouTube: https://bit.ly/TFMYouTube Follow Us on Instagram: @fastingmethod This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

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Semaglutide is a medication that has been gaining popularity for its effectiveness in promoting weight loss. It was originally developed to help manage type 2 diabetes but has since been found to have significant benefits for individuals looking to shed excess pounds. If you’re considering starting treatment with semaglutide for weight loss, there are some important things you need to know before beginning. In this article, we’ll discuss the starting dose of semaglutide, how it works, potential side effects, and other essential information to help you make an informed decision.

What is Semaglutide and How Does it Work?

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of incretin hormones in the body. Incretin hormones help to regulate blood sugar levels, insulin secretion, and feelings of fullness. By activating GLP-1 receptors, semaglutide can help to decrease appetite, improve insulin sensitivity, and promote weight loss.

When taken as a medication for weight loss, semaglutide is usually injected under the skin once a week. The medication is intended to be used in conjunction with a reduced-calorie diet and increased physical activity for best results. It is important to follow your healthcare provider’s instructions closely and attend regular check-ups to monitor your progress.

Before starting treatment with semaglutide, your healthcare provider will determine the appropriate starting dose for you based on factors such as your weight, medical history, and other medications you may be taking. It is essential to follow the prescribed dosing regimen to achieve the desired weight loss outcomes and minimize the risk of potential side effects.

Potential Side Effects of Semaglutide

Like any medication, semaglutide can cause side effects in some individuals. Common side effects may include nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite. These side effects are usually mild to moderate in severity and tend to improve over time as your body adjusts to the medication.

In rare cases, more serious side effects may occur, such as pancreatitis, gallbladder problems, kidney damage, or allergic reactions. It is essential to seek immediate medical attention if you experience symptoms such as severe abdominal pain, persistent vomiting, yellowing of the skin or eyes, or difficulty breathing while taking semaglutide.

Before starting treatment with semaglutide, be sure to discuss any pre-existing medical conditions or concerns with your healthcare provider. It is essential to disclose all medications, supplements, and herbal remedies you are taking to avoid potential interactions that could affect the safety and effectiveness of semaglutide.

Lifestyle Changes and Supportive Care

In addition to taking semaglutide as prescribed, making healthy lifestyle changes is essential for successful weight loss. These changes may include adopting a balanced diet, increasing physical activity, getting an adequate amount of sleep, managing stress, and avoiding unhealthy habits such as smoking and excessive alcohol consumption.

It can also be helpful to seek support from healthcare professionals, such as registered dietitians, exercise physiologists, psychologists, or support groups, to help you stay motivated and on track with your weight loss goals. Remember that weight loss is a journey that requires commitment, dedication, and patience, so be sure to celebrate small victories along the way.

Overall, starting treatment with semaglutide for weight loss can be an effective option for individuals looking to achieve meaningful and sustainable results. By understanding how semaglutide works, potential side effects to watch for, and the importance of making lifestyle changes, you can set yourself up for success on your weight loss journey.

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