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Sources and recommended reading “Grain Brain” David Perlmutter - https://amzn.to/2QJwZZ7 “Brain Maker” David Perlmutter - https://amzn.to/2QN8fit “Keto Clarity” Jimmy Moore - https://amzn.to/2QQbyW3 “Cholesterol Clarity” Jimmy Moore - https://amzn.to/2PUJobi “The Art and Science of Low Carbohydrate Performance” Jeff Volek & Stephen Phinney - https://amzn.to/2QMxfXn “Pure, White and Deadly” by John Yudkin - https://amzn.to/2PWXPf0 “Fat Chance” Robert Lustig - https://amzn.to/2MRX98P I have narrowed down my top 3 to: Green Tea or more specifically its most active ingredient EGCG , Branched Chain Amino Acids perhaps most predominately Leucine, and Medium chain triglycerides namely the 8-carbon saturated fatty acid called Caprylic Acid. Let me explain why! Green Tea I definitely wouldn't say that green tea is the most popular synergistic supplement with a ketogenic diet, but it is highly effective in its ability to reduce the tendency to absorb fat and increase the ability to burn fat. It comes down to the potent fat oxidation that green tea promotes from it being a rich source of polyphenol catechins. In particular EGCG or epigallocatechin gallate is the most active of the catechins in green tea and is primarily responsible for the antioxidant, anti inflammatory, and metabolic effects. To break this down even further the boost in fat metabolism comes from EGCG's direct effect on proteins and phospholipids in the plasma membrane that up regulate mitochondrial function, which we know is the energy factory for all cells in our body, therefore increasing the rate at which fatty acids are metabolized. Or in other words increasing our use of fat to produce energy. In a ketogenic diet where we are primarily depending on fat metabolism for energy, we can see how this boost in fat oxidation can provide improvements in ketone production and can promote further weight loss in the form of body fat or adipose tissue. In addition the naturally occurring caffeine in green tea works synergistically to boost metabolism. BCAA The branched chain amino acids consist of three essential amino acids, meaning they must be consumed and can not be manufactured inside the body, these 3 are: leucine, isoleucine, and valine. We know that in metabolism fueled by glucose protein and amino acid breakdown is inevitable which is what prompts athletes trying to build lean muscle mass to supplement BCAAs. While the ketogenic metabolism has been proven to spare these BCAAs, they also play larger rolls, making their heightened levels even more valuable. As discussed in the "ketogenic effects of muscle building" video, Leucine is able to take on the role of insulin, that is suppressed in a ketogenic diet, and effectively promote muscle protein synthesis. On a smaller cellular level these BCAAs are able to replenish the intermediates for cellular energy cycles, which is a huge benefit in a ketogenic diet were glycolysis is lowered and cellular pyruvate is not as available. In other words BCAAs are able to be broken down into important substrates for cellular energy production, which aids in overall higher energy levels. MCT's Medium Chain Triglycerides are some what of a staple of the ketogenic diet. The structure that allows MCT's to be metabolized quickly, provides pathways for ketone production even in unadapted individuals. The uses of MCTs can range from a daily ketone boost to aiding in the elimination of the tough to deal with side effects of keto adaptation. Tryglycerides in general are made up of a glycerol bound to three fatty acids, and are ingested, stored and more commonly referred to as fats. The differentiating factor between long chain and medium chain triglycerides are the length of the fatty acids that make up their structure. These shorter, medium chain fatty acids, are metabolized in the liver so readily that they are pushed to the front of the line even before simple carbohydrates, resulting in ketone production even when carbs and glucose are present. This is the mechanism that helps decrease the lack of energy and brain fog during the short keto adaptation phase. The MCT's promote ketone production before nutritional ketosis has been reached, making up for the deficit in energy due to the considerable reduction in available energy from carbohydrates when switching to a ketogenic diet. The fact that these MCTs are broken down even before carbohydrates makes them a promising supplement even for a diet regimen including carbs, as a way to reap the benefits of the small increase in ketone production without achieving nutritional ketosis. Keto Science!

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The Most Dangerous DIET SUPPLEMENTS Circulating in the Market that Damage Your LIVER and KIDNEYS | Unhealthy Ingredients in Diet Supplements to Avoid If you've gone to a dietician, you've probably been warned against diet supplements. However, you probably already know that there are healthy and unhealthy ingredients in diet supplements out there. That also means there are tons of unhealthy ingredients in diet supplements to avoid — if you value your health. Healthy diet supplements often involve boosts of protein, green tea, and vitamins. In other words, these supplements are often found in food and are made to help encourage overall health and wellness rather than weight loss in most cases. Unhealthy ingredients in diet supplements are way more common, and they're often are focused on weight loss. In some cases, they're just bad for your wallet and give you the jitters. In other cases, they can end up with a trip to the hospital - or even the morgue. You might wonder how unhealthy or fraudulent diet supplements even make it onto the market. After all, the FDA was made to test out medicines and food, and they wouldn't just turn a blind eye to this stuff, right? Well, not quite. The fact is that diet supplements aren't regulated by the Food and Drug Administration. This is why many dangerous dietary supplements are on the market - and why no one actually seems to notice. So, if you take diet pills or other similar dietary supplements, make sure your supplementation is healthy by taking a look at our list of unhealthy ingredients diet supplements to avoid. Ephedra When it comes to unhealthy ingredients in diet supplements, we might as well start off with one of the few that has been actively banned by the FDA. Ephedra has been linked to a higher risk of heart attack and stroke. Because of multiple deaths, many dietary supplements that had ephedra or ephedra-like ingredients have been investigated and later banned by the FDA. Chaparral Also known as larrea divaricata, larreastat, and Cresote Bush, many people use chaparral supplements as a way to bolster health during bouts of cancer. It's also been known to soothe rashes, and is an active ingredient in many weight loss diet pills. It sounds great, right? There's a reason why chaparral ended up on this list of unhealthy diet supplements: multiple deaths have been linked to the use of chaparral. Symptoms experienced by chaparral users include jaundice and kidney failure. Due to the damage chaparral can unleash on people's livers and kidneys, the FDA advises against using this supplement. Coltsfoot This dandelion-like plant is a favorite among herbalists who use remedies. It's known to reduce symptoms of bronchitis and alleviate coughing. However, it's also a chart topper on many lists of unhealthy ingredients in diet supplements to avoid. As good as it may be for cough relief, Coltsfoot also causes liver and kidney damage. At least one person has been hospitalized from using Coltsfoot in the past, so you might not want to eat this herb. Comfrey Comfrey, when rubbed on certain body parts, gives you a soothing, gentle warmth that can help ease pain and joint issues. It's also been used to help treat menstrual cramps and also smells decently good. However, you shouldn't eat it. Comfrey, when ingested, causes liver damage, kidney damage, and also could be a potential cancer-causer. In terms of unhealthy diet supplements, this one's bad...but only if you actually eat it Aconit Aconite is a plant that goes by a number of different names, including monkshood and wolfsbane. Sellers claim that this dietary supplement could potentially help users with issues arising from gout, inflammation, and joint pain—and to a point, that may be true. However, aconite is called wolfsbane for a reason; it can kill large dogs. In fact, humans who ingest this often will experience nausea, dizziness, heart palpitations, and in larger doses, can easily die as well. Kava Kava This is one of those unhealthy ingredients in diet supplements that should be obvious. People who ingest tea involving kava kava do so in order to alleviate stress. Yes, this is a mind-altering supplement that gives you a "sleepy, content" buzz. However, that's not always good. Too much kava can cause you to fall asleep at the wheel. It also has been linked to liver damage and kidney damage, making it one of the more dangerous supplements on the market. Country Mallow Country Mallow, also known as "silky white mallow," is a pretty common ingredient in a number of weight loss pills. Supplement makers also say that it's great for asthma, bronchitis, and nasal congestion. Much like most other plants on this list, Country Mallow proves that you don't have to be "unnatural" in order to be one of the most unhealthy diet supplements. This plant's ingestion can lead to organ damage, organ failure, sleep disturbances, and death.

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