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This video explains how obesity is fundamentally a brain-based condition—shaped by neurohormonal signals like leptin, ghrelin, and GLP-1—not just a matter of willpower or lifestyle. Drawing on neuroscience and psychiatry, Dr Sanil Rege breaks down how dysregulation in homeostatic and hedonic systems can drive weight gain, resistance to weight loss, and why most diets fail. You'll also learn how GLP-1 receptor agonists like semaglutide and tirzepatide target brain circuits to support sustainable weight management. ⏱️ Chapter Breakdown: Timestamps 0:00 – Introduction: Why obesity is more than lifestyle 0:54 – The hypothalamic control centre: AgRP vs POMC neurons 1:07 – Leptin resistance and the broken satiety signal 1:49 – The two systems driving Hunger - Homeostatic and Hedonic 3:02 – GLP-1 receptor agonists: how they work on the brain 3:53 – Psychiatric medications and metabolic disruption 🎓 Educational Highlights: – Obesity is regulated by both homeostatic (hypothalamic) and hedonic (reward) systems in the brain – Leptin resistance and ghrelin signalling contribute to persistent hunger – Diets often fail because of neurobiological adaptations that resist sustained weight loss – GLP-1 receptor agonists target brain centres involved in satiety, cravings, and inflammation – Certain psychiatric medications exacerbate metabolic dysfunction—an integrative approach is key – Practical tools for clinicians include layered pharmacological strategies and patient-centred care 👨‍⚕️ About the Presenter Dr Sanil Rege is a consultant psychiatrist and educator who has trained over 10,000 mental health professionals. Explore advanced psychiatry and neuroscience-based education at The Academy by Psych Scene. #ObesityTreatment #GLP1 #Semaglutide #NeurobiologyOfObesity #WeightLossScience #PsychiatrySimplified #DrRege #PsychSceneAcademy #LeptinResistance #GLP1Agonists #BrainBasedMedicine Related Videos: 👉 What Fasting Does to Your Brain: https://youtu.be/q_5hZUnmsI4 🎓RESOURCES BY PSYCH SCENE: 🌐The Academy by Psych Scene: PSYCHIATRY EDUCATION REDEFINED https://academy.psychscene.com/ Revolutionary psychiatry learning. 🌐Psych Scene Hub: PSYCHIATRY TEXTBOOK OF THE FUTURE https://psychscenehub.com/ The Hub is devoted to making you a better mental health professional. Our team of academic and clinical experts bring you powerful summaries, videos and interviews in psychiatry and neurosciences. 🌐Psych Interview Online: REAL WORLD SKILLS FOR REAL WORLD SUCCESS https://www.psychinterview.com/ The Psych Interview online courses offer high-quality training to help you improve your psychiatric interview skills through self-study. 🌐Psych Scene Online: THE ONLINE COURSES TO HELP YOU SUCCEED https://ranzcpexams.psychscene.com/ Learn at your own pace with the RANZCP Written Exam prep online courses. 🌐Psych Scene: THE PSYCHIATRY TRAINING EXPERTS https://psychscene.com/ Psych Scene offers specialised training and professional development for Psychiatry Trainees, Psychiatrists, General Practitioners and Mental Health Practitioners. -- 📱SOCIALS Subscribe for weekly videos on Psychiatry and Neuroscience: Facebook: https://m.facebook.com/PsychSceneHub Instagram: https://www.instagram.com/psychiatry.excellence/ – 👋 LET’S CONNECT! Follow Sanil Rege on LinkedIn: https://www.linkedin.com/in/sanilrege

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When it comes to finding a natural and effective way to support weight loss and overall health, Let’s Keto All Natural Gummies have become a popular choice among those looking to incorporate a keto-friendly supplement into their routine. These gummies are made with all-natural ingredients that are designed to help boost metabolism, curb cravings, and support energy levels, making them an ideal option for anyone following a ketogenic diet.

Ingredients

The Let’s Keto All Natural Gummies are made with a blend of high-quality ingredients that are carefully selected to support ketosis and overall health. The key ingredients in these gummies include:

– BHB (Beta-Hydroxybutyrate): BHB is a ketone that helps the body enter a state of ketosis, where it burns fat for energy instead of carbohydrates.

– Green Tea Extract: Green tea extract is known for its antioxidant properties and ability to support metabolism and weight loss.

User Reviews

Many users have reported positive experiences with Let’s Keto All Natural Gummies, noting that they have helped them stay on track with their keto diet and achieve their weight loss goals. Here are some user reviews of the product:

1. “I have been using Let’s Keto All Natural Gummies for a few weeks now, and I have noticed a significant difference in my energy levels and cravings. I feel more focused and motivated to stick to my keto diet, and I have even started to see some weight loss results.” – Sarah

2. “These gummies have been a game-changer for me. I used to struggle with staying in ketosis, but since I started taking them, I have noticed a huge improvement in my energy levels and overall mood. I highly recommend them to anyone following a keto diet.” – Jason

3. “I was skeptical about trying a keto supplement, but Let’s Keto All Natural Gummies have exceeded my expectations. Not only do they taste great, but they have helped me stay on track with my diet and reach my weight loss goals. I will definitely be purchasing them again.” – Emily

FAQ

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2. Are there any side effects associated with these gummies?

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3. How long does it take to see results?

– Results may vary for each individual, but many users report noticing an improvement in energy levels and cravings within the first few weeks of taking Let’s Keto All Natural Gummies. For best results, it is recommended to take them consistently as part of a balanced diet and exercise regimen.

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