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In this candid and heartwarming episode of The Kelly Clarkson Show, Kelly welcomes Jenna Bush Hager and Barbara Bush, who open up about their personal weight loss journeys. The conversation takes an unexpected turn when childhood photos of the Bush twins appear on screen, leading to a discussion about body image and confidence.

The twins recall moments from their youth, with Jenna describing herself as "chubby" back in the day. Kelly immediately disagrees, saying, "You were not." The discussion continues, and it becomes clear that everyone has experienced ups and downs in their weight.

Kelly, who has been open about her own weight loss journey throughout her career, emphasizes the challenges of finding the right jeans when you have a curvy figure and a smaller waist. The audience applauds her honesty and confidence.

The American Idol winner has always been self-assured, even when faced with body-shaming comments. She recalls how people used to comment on her weight during her time on American Idol and how she would shut them down with her self-confidence. Kelly has overcome various obstacles on her path to success, including battling bulimia as a teen because she thought being smaller would help her get better roles in school musicals.

Despite her impressive weight loss, Kelly shares that her weight can fluctuate like a "yo-yo." She humorously mentions her love for kickboxing when she's feeling fit and how sometimes she'd rather enjoy a glass of wine.

This episode serves as a reminder that body image struggles are something many people face, regardless of their fame or success. Kelly Clarkson and the Bush twins share their personal stories, reminding us that self-confidence and self-acceptance are the keys to happiness.

Don't forget to like, comment, and subscribe to The Kelly Clarkson Show for more inspiring and empowering conversations!

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(30 Jan 2025) RESTRICTION SUMMARY: ASSOCIATED PRESS ARCHIVE: Hillerod, Denmark - 26 September 2023 1. Various of diabetes drug Ozempic going through automated packaging line at Novo Nordisk production facility ASSOCIATED PRESS Coral Gables, Florida – 28 January 2025 2. SOUNDBITE (English) Irina Dumitrescu, survey respondent: "I strongly feel that it should be under the supervision of a medical professional and, you know, prescribed." ASSOCIATED PRESS ARCHIVE: Temecula, California – 30 April 2024 3. STILL: Wegovy injectable pens ASSOCIATED PRESS ARCHIVE: Chicago – 20 January 2010 4. STILL: A subject's waist is measured during an obesity prevention study ASSOCIATED PRESS ARCHIVE: Front Royal, Virginia – 1 March 2024 5. STILL Donna Cooper holds up a dosage of Wegovy, a drug used for weight loss, at her home 6. STILL Doses of Wegovy, a drug used for weight loss, are stored in a refrigerator ASSOCIATED PRESS ARCHIVE: Temecula, California – 30 April 2024 7. STILL Stack of Wegovy boxes ASSOCIATED PRESS St. Louis, Missouri – 27 January 2025 8.SOUNDBITE (English) Dr. Kai Jones, Washington University School of Medicine "There's, you know, varied in terms of which private insurance companies cover it and formularies change where medications are covered and they're no longer covered. And that's something we really have to counsel folks about because we know that stopping these medications can often lead to weight regain." ASSOCIATED PRESS ARCHIVE: St. Petersburg, Florida – 7 November 2023 9. Kelly Burns, tirzepatide clinical trial participant, cooks behind an injectable pen of tirzepatide 10. Closeup of vegetable being chopped ASSOCIATED PRESS St. Louis, Missouri – 27 January 2025 11. SOUNDBITE (English) Dr. Kai Jones, Washington University School of Medicine: ++PARTIALLY COVERED++ "And some folks may associate these medications with only weight loss or only those things and not know that they have approval for other medical co-morbidities that are very impactful for people's lives." ASSOCIATED PRESS ARCHIVE: St. Petersburg, Florida – 7 November 2023 12. Various Burns walking down the street for exercise STORYLINE: GLP-1 AGONISTS, COMMONLY REFERRED TO AS WEIGHT-LOSS DRUGS, HAVE SOARED IN POPULARITY IN RECENT YEARS. BUT WHAT DO PEOPLE KNOW AND THINK ABOUT THEM? A NEW POLL FROM THE ASSOCIATED PRESS-NORC CENTER FOR PUBLIC AFFAIRS RESEARCH FINDS THAT ABOUT HALF OF U.S. ADULTS SAY IT’S “VERY GOOD” OR “SOMEWHAT GOOD” FOR ADULTS TO USE WEIGHT-LOSS DRUGS IF THEY ARE STRUGGLING WITH OBESITY OR A WEIGHT-RELATED HEALTH CONDITION. PEOPLE ARE MORE HESITANT WHEN IT COMES TO PRESCRIBING DRUGS TO YOUNGER PEOPLE AGES 12 TO 18, EVEN IF THEY’RE DEALING WITH OBESITY OR A WEIGHT-RELATED CONDITION, AND MOST AMERICANS DON’T THINK IT’S A GOOD IDEA FOR THESE DRUGS TO BE USED TO LOSE WEIGHT IF A PERSON ISN’T OBESE. SOUNDBITE (English) Irina Dumitrescu, survey respondent "I strongly feel that it should be under the supervision of a medical professional and, you know, prescribed." ABOUT HALF OF AMERICANS ALSO FAVOR MEDICAID AND MEDICARE COVERING WEIGHT LOSS DRUG PRESCRIPTIONS FOR PEOPLE WITH OBESITY. CURRENTLY, COVERAGE IN THE U.S. OF THESE DRUGS REMAINS SCATTERED. SOME LARGE COMPANIES AND MEDICAID PROGRAMS ARE ADDING COVERAGE. BUT MANY OTHER EMPLOYERS AND HEALTH INSURERS ARE SCALING BACK, AND MEDICARE DOESN’T COVER THE DRUGS AT ALL. SOUNDBITE (English) Dr. Kai Jones, Washington University School of Medicine EXPERTS ALSO WANT PEOPLE TO UNDERSTAND THAT OBESITY CAN BE COMPLICATED TO TREAT, AND THAT THESE DRUGS CAN HAVE OTHER IMPACTS AS WELL. Find out more about AP Archive: http://www.aparchive.com/HowWeWork Twitter: https://twitter.com/AP_Archive Facebook: https://www.facebook.com/APArchives ​​ Instagram: https://www.instagram.com/APNews/ You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/31aa5baa1f8e427b827ba1d711b5b911

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In the dynamic field of pharmaceutical development, GLP-1 agonists are leading a transformative approach to managing obesity and type-2 diabetes. A recent webinar detailed new endpoint strategies designed to distinguish GLP-1 agonists in a competitive market. This engaging session provided insights into the latest FDA draft guidance and the role of digital endpoints in drug development. Topics discussed include: Navigating FDA Guidance for Weight Reduction: The session was timely, following the FDA's new draft guidance for weight reduction drug development. Industry experts shared insights on complying with these recommendations and explored innovative strategies to enhance drug differentiation. Clinical Adjudication and Safety Strategies: Highlighting the importance of clinical adjudication, the webinar emphasized methods for achieving unbiased and consistent event classifications. This approach not only aligns with regulatory standards but also ensures accurate data evaluation, crucial for drug safety and efficacy. Innovative Imaging Techniques for Endpoints: Advances in medical imaging, including DEXA and MRI, provide significant data on body composition changes. These techniques are essential for understanding the effects of GLP-1 agonists on lean muscle mass and adiposity, offering a critical dimension to clinical trial assessments. Discover more about GLP-1 agonist development and explore the future of drug differentiation with innovative endpoint strategies. Join us to delve deeper into the cutting-edge methodologies redefining clinical research today.

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