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REFERENCE for Curious Interested Listeners & Physicians 48,25mar In Part 2 of our deep dive into Mounjaro vs. Ozempic, we’re busting myths and uncovering what doctors aren’t always saying. Here’s what we’ll cover: • Myth 1: “All GLP-1 drugs are the same.” • Reality: Ozempic targets a single pathway, while Mounjaro works on two—leading to potential greater weight loss in some, but it’s not a one-size-fits-all. • Myth 2: “These drugs only make you eat less.” • Reality: They also influence the brain’s reward system, reducing cravings and the emotional drivers of eating, not just physical hunger. We’ll break down how these medications work, the real-world impact, and why individual responses vary. Stay tuned Part 3 for more insights into what doctors might not be telling you about these weight loss treatments! 1. Animal Studies Alhadeff AL, Rupprecht LE, Hayes MR. (2012). Glucagon-like peptide-1 receptor signaling in the ventral tegmental area attenuates food intake. Journal of Neuroscience, 32(25), 8112-8120. Showed GLP-1 drugs reduce food-seeking behavior by acting on brain reward areas. 2. Brain Reward Pathways Dickson SL, Shirazi RH, Hansson C, et al. (2012). The role of GLP‑1 receptor activation in the central regulation of energy balance and reward. Physiology & Behavior, 106(2), 231–238. Explains how GLP-1 receptors in the brain influence eating for pleasure, not just hunger. 3. Incretin Hormones Review Nauck MA & Meier JJ. (2018). Incretin hormones: Their role in health and disease. Diabetes, Obesity and Metabolism. Details the dual role of GLP-1 in gut and brain signaling. 4. The SURPASS-2 Trial Jastreboff, A. M., et al. (2022). Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2): A Randomized, Open-Label, Parallel-Group, Phase 3 Trial. This study and provided weight loss data for both tirzepatide (Mounjaro) and semaglutide (Ozempic). 5. The SURPASS Clinical Trials (Review and Meta-Analysis) Frías, J. P., et al. (2022). Insights from the SURPASS Clinical Trials: A Systematic Review and Meta-Analysis of Tirzepatide in Type 2 Diabetes. Diabetes, Obesity and Metabolism. Discusses how the additional GIP receptor activity might contribute to enhanced weight loss. 6. Eli Lilly (Mounjaro) https://www.lilly.com/news/media/media-kits/mounjaro https://mounjaro.lilly.com 7. Novo Nordisk (Ozempic) https://www.novonordisk.com.au/our-products-for-healthcare-professionals.html https://rss.medsinfo.com.au/no/pi.cfm?product=nopozemp

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Here The Link: http://WeightLossFastSystem.com/Guaranteed-Fat-Loss For Men: http://WeightLossFastSystem.com/Lose-Fat-Guaranteed When you look at people who lose weight easily and have great bods, the amount of water they drink is a key factor. You'll be amazed at the benefits that drinking the correct amount of water can bring. Studies show that almost half of the population drinks less water than the daily requirement, leading people to a permanent state of dehydration. So, let's begin by reviewing the negative effects of drinking less water than you need - starting with the ones that are preventing you from losing weight and are making you store fat more easily. 9 Devastating Effects of Drinking Too Little Water: 1. Headache. 2. Stomach ache and acidity. 3. Toxin accumulation. 4. Constipation. 5. Increased appetite: The body tends to boost appetite as a sign of dehydration, making it very hard to follow a diet properly. 6. Difficulty to turn carbohydrates into energy: In order to metabolize 1 gram of carbohydrates, 3 grams of water are needed; otherwise, carbs easily get stored as body fat. 7. Increased risk of fluid retention: Due to lack of water, your body retains and stores as much as it can from the little water you give it. The result is a flaccid appearance and weight gain. 8. Stalled weight loss and fat burn: Water plays an essential role in fat metabolism. When the body systems are working properly, the liver transforms stored body fat into energy. But when in a dehydrated state, it's more difficult for the kidneys to cleanse the blood. The liver stops burning fat to help the kidneys do their job. 9. Slowed down metabolism: As the digestive system is unable to carry out its processes correctly, the capacity to burn calories is drastically reduced in consequence. Under these circumstances, weight loss is almost impossible, regardless the amount of exercise you do. I think that now that you know these 9 negative effects, you have an advantage over people who are unaware of this information. Now you know why people who drink enough water burn fat and lose weight more easily than those who don't. But, what is the correct water intake to lose weight and keep my body burning fat? I recommend starting with a minimum of 8 glasses a day, however, the correct amount of water you should take will increase depending on how overweight you are. Use the following indicator as a rule of thumb: If your urine is not transparent, you need to drink more water. The sole exception to this rule is when you first get up in the morning, because urine concentrates overnight. Generally, the optimal amount of water needed varies roughly between a gallon and a gallon and a half, daily. Drink one or two glasses before every meal, and carry a gallon jug with you whenever you work out or leave your home. Another important thing to take into account is to get mineral or bottled water if the tap water in your area is not safe enough to drink. Another option is to purchase a purifying system. Avoid drinking artificial juice, sodas and other sugary drinks. They are loaded with preservatives and calories, but don't provide any nutrients. They will not only make you put on fat, but their side effects also damage your body. Remember that the cleaner you keep it, the easier it will be for your body to lose weight. I hope you liked this video, and found it helpful! Remember to visit the link below if you are looking for more valuable information. Until next time! http://weightlossfastsystem.com/how-much-water-to-drink-to-lose-weight-2/

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