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Understanding GLP1 and Its Effects Exploring the impact of GLP1 on dopamine pathways and appetite control. #Health #GLP1 GLP1 stands for Glucagon-Like Peptide-1, which is a hormone produced in the gut that plays a crucial role in glucose metabolism and appetite regulation. When released into the bloodstream after a meal, GLP1 acts on multiple organs, including the brain, to control blood sugar levels and suppress appetite. One of the important ways GLP1 affects the brain is by influencing dopamine pathways. Dopamine is a neurotransmitter associated with pleasure and reward, and it plays a role in regulating food intake. GLP1 has been found to increase the release of dopamine in the brain's reward centers, which can lead to a decrease in cravings for high-calorie foods. Furthermore, GLP1 also acts on specific brain regions involved in appetite control. It communicates with the hypothalamus, a region responsible for integrating signals related to hunger and satiety. GLP1 activates certain neurons in the hypothalamus that suppress appetite and promote a feeling of fullness. In addition to its impact on dopamine pathways and appetite control, GLP1 has other beneficial effects on health. It stimulates the pancreas to produce more insulin, a hormone that lowers blood sugar levels. This is particularly important for people with type 2 diabetes, as GLP1-based medications have been developed to help manage blood sugar levels. Moreover, GLP1 slows down the rate at which the stomach empties, prolonging the feeling of fullness after a meal. This can lead to reduced food intake and weight loss, making GLP1 an attractive target for the treatment of obesity. GLP1-based medications, such as GLP1 receptor agonists, have been developed to mimic the effects of GLP1 and are used in the treatment of both type 2 diabetes and obesity. These medications help regulate blood sugar levels, promote weight loss, and reduce food intake by targeting GLP1 receptors in the body. In conclusion, GLP1 is a hormone that plays a crucial role in glucose metabolism and appetite regulation. Its effects on dopamine pathways and appetite control contribute to the regulation of food intake and can be targeted by medications for the treatment of conditions like type 2 diabetes and obesity.

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Bestselling author Abel James joins us on the podcast. We discuss the misconceptions of eating fat, eating bugs in Thailand, and his new book The Wild Diet.

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