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When drugs like Wegovy and Ozempic hit the market, they were hailed as revolutionary weight loss solutions. For many, these GLP-1 receptor agonists delivered on their promise, helping people shed significant pounds and improve their health. But for others, the reality is far more frustrating. As many as 1 in 5 people using these medications see little to no results, leaving them disheartened and questioning if the hype is real. If you’ve wondered why these “miracle” drugs don’t work for everyone—or if you’re one of the unlucky nonresponders—this article will explore the science, the solutions, and the hope behind finding what works for you. --- #### **The Science Behind GLP-1 Drugs** GLP-1 receptor agonists like Wegovy and Ozempic mimic a natural hormone in the body, glucagon-like peptide 1. This hormone helps regulate appetite, blood sugar, and energy balance by signaling the brain to feel full. For most people, this process effectively reduces appetite, helping them eat less and lose weight. Clinical trials show that patients can lose 15-22% of their body weight, but these impressive results don’t tell the whole story. #### **Why They Fail for Some** Approximately 10-20% of users fall into the category of “nonresponders,” losing less than 5% of their body weight. Experts believe genetics, hormones, and brain function play significant roles. Dr. Fatima Cody Stanford, an obesity expert, explains, “This is a disease that stems from the brain, and the dysfunction may not be the same for every patient.” Other factors—like medical conditions, sleep apnea, or medications such as antidepressants or steroids—can also blunt the effectiveness of GLP-1 drugs. --- #### **High Hopes, Deep Disappointments** The promise of these drugs has created soaring expectations, but for those who don’t see results, the letdown can be devastating. Dr. Katherine Saunders, an obesity specialist, highlights this emotional roller coaster: “With such high expectations, there’s so much room for disappointment.” Patients like Danielle Griffin, who hoped Wegovy would help her lose 70 pounds, find themselves feeling defeated when the scale barely moves. Despite following her doctor’s advice, exercising, and maintaining a healthy diet, Griffin only lost 13 pounds over a year and a half. #### **The Ripple Effect of Disappointment** This disappointment isn’t just about weight loss. For many, these drugs represent hope—a chance to improve their health and quality of life. When they don’t work, it can feel like hitting a wall, leaving patients questioning their options and their own efforts. --- #### **Switching Medications** If one GLP-1 drug doesn’t work, another might. The class of drugs includes different formulations, each targeting slightly different pathways in the body. Danielle Griffin, for example, transitioned from Wegovy to Zepbound, which also targets a second hormone pathway. In just three months, she’s seen slow but steady progress, losing 7 pounds. #### **Exploring Older Medications** For some patients, older weight loss drugs outside the GLP-1 category may prove more effective. Medications like phentermine or naltrexone-bupropion can still offer significant benefits under the guidance of a healthcare professional. --- --- The promise of GLP-1 drugs like Wegovy and Ozempic is real, but it’s not universal. For the 1 in 5 people who don’t respond as expected, the journey can be frustrating—but it’s far from over. Whether it’s switching medications, addressing lifestyle factors, or redefining your goals, there’s always another path forward. Remember, obesity is a complex condition that requires comprehensive care. Partner with healthcare professionals, stay open to trying new strategies, and focus on the bigger picture of your health and well-being. If you’ve found this article helpful or relatable, let us know in the comments: Have you tried GLP-1 drugs? What’s your experience been like? Don’t forget to **like, share, and subscribe** for more content about health, wellness, and finding solutions that work for you!

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If you’re following a keto diet, you may know that getting all the essential minerals your body needs can be a challenge. That’s where K3 Mineral Gummies come in. These mineral-rich gummies are designed to support your keto lifestyle by providing key minerals that are often lacking in the diet. Whether you’re new to the keto diet or a seasoned veteran, K3 Mineral Gummies can help you stay on track and feel your best.

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K3 Mineral Gummies are specifically formulated to provide essential minerals that are often lacking in a keto diet. Each gummy is packed with magnesium, potassium, and calcium – three key minerals that play a crucial role in overall health and well-being. These minerals are important for maintaining proper nerve and muscle function, supporting bone health, and regulating fluid balance in the body. By incorporating K3 Mineral Gummies into your daily routine, you can ensure that you’re getting all the mineral support you need to thrive on a keto diet.

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There are many benefits to incorporating K3 Mineral Gummies into your daily routine. One of the key benefits is their ability to help you maintain electrolyte balance on a keto diet. Electrolytes, such as magnesium and potassium, are essential for proper nerve and muscle function, as well as hydration. By supplementing with K3 Mineral Gummies, you can ensure that you’re meeting your electrolyte needs and avoiding common keto flu symptoms like fatigue and muscle cramps.

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Adding K3 Mineral Gummies to your daily routine is easy. Simply take the recommended dose each day, either on its own or as part of a snack. The gummies can be taken at any time of day, so you can choose a time that works best for you. Some people prefer to take them in the morning with breakfast, while others like to have them as a mid-day pick-me-up. However you choose to incorporate them into your routine, you can rest assured that you’re giving your body the mineral support it needs to thrive.

If you’re new to taking supplements, it’s always a good idea to consult with your healthcare provider before adding anything new to your routine. They can help you determine the right dosage for your individual needs and ensure that there are no interactions with any medications you may be taking. With their guidance, you can feel confident in adding K3 Mineral Gummies to your daily regimen.

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Yes, K3 Mineral Gummies are suitable for vegetarians and vegans, as they do not contain any animal-derived ingredients.

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K3 Mineral Gummies are designed for adults, but children over the age of 4 can also take them. It’s always best to consult with a healthcare provider before giving any supplements to children.

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In this video, I will share with you the science behind these “new miracle drugs” - Ozempic and Wegovy and whether you can get an unusual appearence called 'Ozempic Face'. These are both a drug called semaglutide, and work by mimicking the effects of a hormone called (GLP-1) in the body, which helps to regulate blood sugar levels and aids in weight loss. Ozempic was given to Diabetes patients, and after reports of considerable weight loss, the same laboratory created Wegovy, the same medication but a version made for non-diabetes to lose weight. People taking Ozempic/ Wegovy have reported these Unusual symptoms: - A hollowed-out appearance on their face - More wrinkles and lines across, making them look older - Loose and saggy skin And we hear all over the media the so-called “ozempic face”. However, its more of a side effect of losing weight quickly, here is why... When we lose weight, we start to lose the stores of fat around the body (the classic belly fat), but we also lose fat around organs and across our face. If the weight loss occurs very quickly, our skin may not have enough time to adjust to the changes in our body, causing loose, sagging skin, especially in areas where there was a lot of fat or muscle mass before the weight loss. This would occur to anyone going to a sudden loss of weight and is not linked to a specific side effect of a drug. Would you like to be healthy and learn from my reflections as a doctor? Join our Newsletter 💻Twice monthly snippets on 🌿 Healthy living🌿🧠 Well-being 🧠🤗 Happiness 🤗 ​https://bit.ly/2ZhCh6K - see y'all there! DISCLAIMER: ** The information in this video is intended to serve as educational information and is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/advanced practice provider. ** If you are new here, welcome, I'm Doctor Khalid and I try and simplify medicine and health topics. I would love for you to stay for future videos 📥 SUBSCRIBE ... hit the BELL 🔔 https://bit.ly/3pZFz6O What I used to make this video: iPad Pro 2020 12.9" : https://amzn.to/3it5Pn6 Apple Magic Keyboard: https://amzn.to/3gm41ue Apple Pencil 2: https://amzn.to/31GmY6M HP Desktop computer + Premier Pro My Gear: Sony A6400 DSLR: https://amzn.to/3ivF7dp Sigma 16mm f/1.4: https://amzn.to/3gpqczA Tripod: https://amzn.to/2D7O0d6 💻 Drop me a COMMENT below and share your ideas. 👍 LIKE the video - if you liked it :) 🗣 SHARE with your friends. 📥 SUBSCRIBE ... hit the BELL 🔔 🔔 This activates post notifications so you're first to see my next video! 🔔 DM me your questions on Instagram - I love hearing from you guys and always try my best to answer your questions and suggestions. Drop-in on some of my other channels for similar content: Tik Tok ➤ https://www.tiktok.com/@doctor.khalid?lang=en INSTA ➤ https://www.instagram.com/khalidzalmay TWITTER ➤ http://twitter.com/khalidzalmay