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#바이오 #신약 #한국 #바이오주 #바이오기업 #생명과학 #정보 #과학 #삼천당제약 #삼천당제약전망 #삼천당제약주식 #삼천당제약분석 #디앤디파마텍 #디앤디 #dnd #비만약 #비만치료제 #비만치료제관련주 #의약품 #제약바이오 #비만치료 #이슈 #일라이릴리 #노보노디스크 #위고비 #wegovy #saxenda #삭센다 #spass #science #novonordisk #elililly #pfizer #glp #glp1forweightloss #glp1weightloss #glp1medication @Jeonbashi 1. 경구용 비만치료제 시장, 게임 체인저가 될 수 있을까? 최근 제약·바이오 업계에서 가장 주목받고 있는 키워드 중 하나가 바로 경구용 비만치료제다. 전 세계적으로 비만 환자가 급증하면서 관련 치료제 시장도 빠르게 성장하고 있는데, 현재 글로벌 비만치료제 시장 규모는 약 100조 원에 달하며, 2030년에는 무려 318조 원 규모까지 확대될 것으로 예상된다. 기존의 GLP-1 (Glucagon-like Peptide-1) 기반 비만치료제는 체중 감량 효과가 뛰어나지만, 대부분 주사제로 개발되어 있어 환자들이 지속적으로 자신의 복부나 허벅지에 주사를 놓아야 하는 불편함이 있었다. 그러나 최근 글로벌 제약사들이 알약 형태로 복용할 수 있는 경구용 GLP-1 제제 개발에 성공하면서 비만 치료제 시장의 판도가 바뀌고 있다. 경구용 비만치료제는 주사제 대비 복용이 간편하고, 환자의 심리적 부담을 줄여 치료 순응도를 높일 수 있다는 점에서 더욱 주목받고 있다. 2. 글로벌 제약사들의 움직임과 시장 전망 현재 노보노디스크(Novo Nordisk), 일라이릴리(Eli Lilly and Company), 화이자(Pfizer Inc.), 로슈(Roche) 등 글로벌 빅파마들은 경구용 비만치료제 개발에 박차를 가하고 있다. 특히 노보노디스크는 이미 ‘리벨서스(RYBELSUS)’라는 경구용 GLP-1 제제를 개발해 2019년 FDA 승인을 받았지만, 이는 당뇨병 치료제로만 허가된 상태다. 비만 치료 목적으로 사용하기 위해서는 추가적인 연구와 임상이 필요한 상황이다. 일라이릴리 역시 경구형 GLP-1 후보물질을 개발 중이며, 현재 임상 3상 단계에 접어든 상태다. 화이자와 로슈 또한 GLP-1 계열뿐만 아니라, 새로운 기전을 활용한 경구용 비만치료제 개발을 진행하고 있어 시장의 경쟁이 더욱 치열해지고 있다. 전문가들은 향후 3~5년 내에 경구용 비만치료제가 본격적으로 상용화될 가능성이 높다고 보고 있으며, 이로 인해 기존 주사제 중심의 비만치료제 시장이 빠르게 재편될 것으로 예상된다. 3. 국내 제약사들의 도전과 경쟁력 이러한 변화 속에서 국내 제약 바이오 기업들도 경구용 비만치료제 시장 진입을 위한 연구개발에 속도를 내고 있다. 그중에서도 특히 삼천당제약과 디앤디파마텍이 주목받고 있다. 3-1. 삼천당제약, 신기술로 시장에 도전 삼천당제약은 기존 안과 치료제 전문 제약사로 알려져 있지만, 최근 경구용 GLP-1 비만치료제 개발에 본격적으로 뛰어들었다. 이 회사는 ‘S-PASS 플랫폼’이라는 독자적인 기술을 활용해 주사제를 알약 형태로 전환하는 연구를 진행 중이며, ‘SCD506’이라는 경구용 GLP-1 제네릭 치료제를 개발하고 있다. 또한 미국과 일본 등 글로벌 기업들과 협력하여 독점 판매 계약을 체결하는 등 해외 시장 진출도 적극적으로 추진 중이다. 다만, 이 기술이 실질적으로 효과를 발휘할 수 있을지에 대한 검증이 아직 충분하지 않으며, 현재 임상 1상 진입 전 단계에 있어 개발 속도와 성공 가능성에 대한 신중한 접근이 필요하다. 3-2. 디앤디파마텍(D&D Pharmatech), 독자 기술로 차별화 디앤디파마텍은 ‘오랄링크(ORALINK)’라는 자체 기술을 기반으로 펩타이드 기반 약물을 경구용으로 전환하는 연구를 진행하고 있다. 이미 미국 바이오기업 멧세라와 기술 이전 계약을 체결하며 글로벌 시장에서도 기술력을 인정받고 있으며, 현재 미국에서 임상 1상을 진행 중이다. 하지만, 아직 임상 초기 단계이기 때문에 불확실성이 크고, 글로벌 빅파마들과의 경쟁에서 살아남기 위해서는 추가적인 연구개발과 차별화된 전략이 필요하다. 4. 경구용 비만치료제 시장의 과제와 전망 경구용 비만치료제가 성공적으로 시장에 안착하기 위해서는 몇 가지 해결해야 할 기술적 과제가 있다. 대표적인 문제는 흡수율과 효과성의 입증이다. 현재까지 경구용 GLP-1 제제의 생체이용률은 1% 이하로 매우 낮으며, 복용 후 일정 시간 금식을 해야 하는 불편함도 있다. 이러한 문제를 해결하기 위해서는 약물의 흡수율을 높이면서도 체중 감량 효과를 유지할 수 있는 새로운 제형 기술이 필요하다. 또한, 글로벌 빅파마들이 막대한 연구개발 비용을 투자하며 시장을 선점하고 있는 만큼, 국내 기업들이 경쟁력을 갖추기 위해서는 기술력뿐만 아니라, 해외 시장 진출 전략도 필수적이다. 5. 앞으로의 전망, 그리고 여러분의 생각은? 경구용 GLP-1 비만치료제는 앞으로 비만 치료의 패러다임을 완전히 바꿀 게임체인저가 될 가능성이 높다. 하지만, 글로벌 제약사들이 빠르게 시장을 선점하는 가운데, 국내 기업들이 이를 따라잡을 수 있을지는 여전히 불확실하다. 여러분은 삼천당제약과 디앤디파마텍이 글로벌 시장에서 경쟁력을 가질 수 있다고 보시나요? 댓글로 여러분의 생각을 남겨주시고, 영상이 유익했다면 구독과 좋아요, 알림 설정도 부탁드린다. 영상 제작에 큰 힘이 됩니다! 앞으로도 흥미로운 제약·바이오 소식을 전해드리겠다. 감사합니다 :)

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Weight loss can be a challenging journey for many individuals, but with the help of medications such as semaglutide, it becomes more achievable. Semaglutide is a prescription medication that has been shown to be effective in aiding weight loss when combined with a healthy diet and exercise. However, once you have achieved your weight loss goals with semaglutide, it is important to maintain your results in the long term. This article will provide you with tips on how to maintain weight loss after semaglutide treatment.

Stay Consistent with Healthy Eating Habits

One of the most important factors in maintaining weight loss is to stay consistent with healthy eating habits. This includes eating a balanced diet that is rich in fruits, vegetables, lean proteins, and whole grains. It is important to avoid processed foods, sugary snacks, and high-fat meals, as these can lead to weight gain. Instead, focus on portion control and mindful eating to ensure that you are consuming the right amount of calories for your body’s needs.

Additionally, it is essential to stay hydrated by drinking plenty of water throughout the day. Water helps to keep you feeling full and can prevent overeating. Try to limit your intake of sugary beverages such as soda and juice, as these can add unnecessary calories to your diet.

Planning your meals ahead of time can also be beneficial in maintaining weight loss. By preparing healthy meals and snacks in advance, you can avoid the temptation of unhealthy options when you are hungry. Meal prepping can also help you stay on track with your weight loss goals and prevent impulsive eating decisions.

Engage in Regular Physical Activity

In addition to maintaining a healthy diet, regular physical activity is essential for maintaining weight loss after semaglutide treatment. Aim to engage in at least 150 minutes of moderate-intensity exercise each week, such as brisk walking, cycling, or swimming. You can also incorporate strength training exercises into your routine to build muscle mass and boost your metabolism.

Find activities that you enjoy and make them a regular part of your routine. Whether it’s dancing, yoga, or playing a sport, staying active can help you burn calories and maintain your weight loss results. Remember to listen to your body and give yourself rest days when needed to prevent burnout and injuries.

Setting realistic fitness goals can also help you stay motivated and committed to your weight loss maintenance plan. Whether it’s running a 5k, lifting heavier weights, or mastering a new workout routine, having goals to strive for can keep you focused and on track.

Monitor Your Progress and Adjust as Needed

Tracking your progress is crucial for maintaining weight loss after semaglutide treatment. Keep a food journal to record your meals and snacks, as well as your feelings and emotions when eating. This can help you identify patterns and triggers that may lead to overeating or unhealthy food choices.

Weigh yourself regularly to stay accountable and catch any weight gain early on. However, remember that weight fluctuates naturally and does not always reflect fat gain. Instead of solely relying on the scale, take measurements of your body, track your fitness performance, and pay attention to how your clothes fit to gauge your progress.

If you find that you are struggling to maintain your weight loss, don’t be afraid to seek support from a healthcare provider, nutritionist, or therapist. They can help you identify any underlying issues that may be hindering your progress and provide you with the tools and resources to overcome them.

Practice Mindful Eating and Stress Management

Mindful eating is a practice that involves being present and aware of your food choices, eating habits, and hunger cues. By paying attention to how your body feels before, during, and after eating, you can make better decisions about what and how much to eat. Avoid distractions such as phones, computers, or TV while eating to focus on your meal and savor each bite.

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Stay Committed to Long-Term Lifestyle Changes

Maintaining weight loss after semaglutide treatment requires a long-term commitment to healthy lifestyle changes. Remember that weight loss is not a quick fix but a journey that requires consistency, patience, and perseverance. Instead of focusing on a number on the scale, aim to improve your overall health, well-being, and quality of life.

Stay motivated by celebrating your successes, no matter how small they may seem. Whether it’s fitting into a smaller size of jeans, completing a challenging workout, or cooking a nutritious meal from scratch, acknowledge your achievements and use them as motivation to continue your journey. Surround yourself with a supportive community of friends, family, or online groups who can cheer you on and provide encouragement along the way.

Remember that setbacks are a natural part of any weight loss journey, and it’s important not to be too hard on yourself if you slip up. Instead of viewing setbacks as failures, see them as learning opportunities to assess what went wrong and how you can do better next time. With dedication, commitment, and a positive mindset, you can maintain your weight loss after semaglutide treatment and lead a healthier, happier life.

After reading this article, you should have a better understanding of how to maintain weight loss after semaglutide treatment. By staying consistent with healthy eating habits, engaging in regular physical activity, monitoring your progress, practicing mindful eating and stress management, and committing to long-term lifestyle changes, you can help ensure that your weight loss results are sustainable in the long run. Remember that maintaining weight loss is a journey that requires dedication, patience, and self-care, but with the right tools and support, you can achieve your goals and lead a healthier, happier life.

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When it comes to weight loss medications, Semaglutide has been making waves in the medical community. This medication, originally approved for managing type 2 diabetes, has recently been approved for weight loss in higher doses. With its effectiveness in aiding weight loss, many individuals have started to wonder about the potential interactions between Semaglutide and alcohol. Can you drink alcohol while taking Semaglutide for weight loss? In this article, we will explore the considerations and potential risks associated with combining alcohol and Semaglutide.

Understanding Semaglutide for Weight Loss

Semaglutide is a medication that belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It works by mimicking the effects of GLP-1, a hormone that helps regulate blood sugar levels and reduces appetite. In lower doses, Semaglutide is used for managing type 2 diabetes. However, in higher doses, it has been found to be effective in aiding weight loss in individuals with obesity or overweight.

When taken as prescribed, Semaglutide can help individuals lose weight by reducing their appetite, increasing feelings of fullness, and slowing down gastric emptying. It is typically prescribed as part of a comprehensive weight loss program that includes diet and exercise. However, like any medication, Semaglutide also comes with potential side effects and interactions that individuals should be aware of.

One common question that arises is whether it is safe to consume alcohol while taking Semaglutide for weight loss. Alcohol consumption is a common social activity for many individuals, and it is essential to understand how it may interact with Semaglutide. Let’s delve into the potential considerations and risks associated with drinking alcohol while on Semaglutide therapy.

Potential Interactions between Alcohol and Semaglutide

Alcohol consumption can have various effects on the body, including interactions with medications. When it comes to Semaglutide, there are a few key considerations to keep in mind. Firstly, alcohol is known to lower blood sugar levels, especially in individuals with diabetes. Since Semaglutide also works to lower blood sugar levels, combining alcohol with this medication may increase the risk of hypoglycemia (low blood sugar).

Additionally, alcohol consumption can affect liver function, and Semaglutide is metabolized in the liver. Drinking alcohol while taking Semaglutide may put additional stress on the liver and affect how the medication is processed in the body. This could potentially impact the effectiveness of Semaglutide in aiding weight loss.

Furthermore, alcohol may also contribute to weight gain and hinder weight loss efforts. Alcoholic beverages are often high in empty calories and can lead to increased appetite and poor food choices. Combining alcohol with a weight loss medication like Semaglutide may counteract the intended effects of the medication and make it more challenging to achieve weight loss goals.

Considerations for Individuals Taking Semaglutide

It is essential for individuals taking Semaglutide for weight loss to discuss alcohol consumption with their healthcare provider. Your doctor can provide personalized advice based on your medical history, current medications, and weight loss goals. They may recommend limiting or avoiding alcohol while on Semaglutide therapy to minimize potential risks and maximize the effectiveness of the medication.

If you choose to consume alcohol while taking Semaglutide, it is crucial to do so in moderation and monitor your blood sugar levels closely. Be aware of the signs and symptoms of hypoglycemia, such as dizziness, confusion, sweating, and shaking. If you experience any of these symptoms, it is important to treat low blood sugar promptly by consuming fast-acting carbohydrates.

Additionally, pay attention to how alcohol affects your weight loss progress while on Semaglutide. Keep track of your alcohol intake, food choices, and weight fluctuations to determine if alcohol is hindering your weight loss efforts. If you find that alcohol is impacting your progress, consider reducing or eliminating it from your routine to optimize the benefits of Semaglutide.

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