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(USMLE topics) Methamphetamine: mechanism of action, short-term and long-term effects, addiction and overdose. Purchase a license to download a non-watermarked copy of this video on AlilaMedicalMedia(dot)com ©Alila Medical Media. All rights reserved. Voice by: Ashley Fleming All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Methamphetamine, also called meth or crystal meth, among other names, is a psychostimulant drug mainly known for its recreational use. Methamphetamine is chemically similar to amphetamine, a drug used to treat attention-deficit hyperactivity disorder, obesity and narcolepsy; but being more potent and highly addictive, methamphetamine is rarely prescribed for medical treatments. Most commonly, the drug is produced illegally, from pseudoephedrine, an ingredient in cold medicines. It can exist as white powder, pills, or bluish-white crystals, and can be consumed by swallowing, smoking, snorting, or injecting. Methamphetamine acts to increase the amount of a neurotransmitter called dopamine in the brain. Dopamine is at the basis of the brain reward pathway, which is designed to “reward” the body for important behaviors that are essential for survival, such as feeding when hungry. Engaging in enjoyable activities causes dopamine release from dopamine-producing neurons into a space between neurons, where it binds to and stimulates its receptors on the neighboring neuron. This stimulation is believed to produce pleasurable feelings or rewarding effect. Normally, dopamine molecules are promptly cleared from the synaptic space to ensure that the postsynaptic neurons are not over-stimulated. This is possible thanks to the action of dopamine-transporter, which channels dopamine back to the transmitting neuron. Methamphetamine binds to dopamine-transporter and blocks dopamine re-uptake. In addition, it can enter the transmitting neuron and trigger more dopamine release. The result is that dopamine builds-up in the synapse to a much greater amount than normal. This produces a continuous over-stimulation of receiving neurons and is responsible for the prolonged and intense euphoria experienced by drug users. At a low dose, methamphetamine stimulates the brain and can elevate mood and alertness; and by accelerating heart rate and breathing rate, it increases energy in fatigued individuals. It also reduces appetite and promotes weight loss. These seemingly “positive” effects keep users coming back for more, eventually leading to addiction and potential overdose. Long-term drug users may experience extreme weight loss, severe dental damage, and constant hyperactivity which results in anxiety, sleeping disorders and violent behaviors. Overdose takes the drug’s effects to the extreme and can cause psychosis, heart attacks, seizures, strokes, organ failures, and even death. Currently, there is no approved pharmacological treatment for methamphetamine addiction; the most effective treatments are cognitive behavioral therapies.

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Shaun T Reveals His Weight-Loss Secrets | Oz Weight Loss Celebrity fitness trainer Shaun T reveals how he lost 50 pounds by dancing, his delicious diet swaps, and more secrets to slim-down success. Welcome to the official Dr. Oz YouTube Channel. Please enjoy all the exciting videos that will teach you about health and wellness, including beauty tips, recipes, supplements, happy relationships, smart finances, and much more to live "The Good Life". Subscribe to Dr. Oz's official YouTube channel: https://bit.ly/1QhiDuv Read Dr. Oz's blogs at iHerb: https://www.iherb.com/experts/dr-mehmet-oz

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The new year brings new opportunities to improve our health and wellness regimen, and it doesn’t have to be overwhelming or cost a fortune. Whether you are looking for help to reach your weight loss goals or looking for blood sugar support, Dr. Stephanie Redmond, PharmD, CDE, BC-ADM is here with the latest innovation in natural, prescription-free supplement options for hormone and metabolic health, including a natural GLP-1 option. With the current craze about GLP-1 products such as Ozempic, what exactly is GLP-1? GLP-1 as a hormone target has been a breakthrough in the weight loss industry, and there is incredible research about how this gut hormone is crucial in regulating body weight. What does GLP-1 do? When we eat food, our intestinal cells make GLP-1 as a signal to our brain and body that we are full, to stop eating, and to stop being hungry. But our body’s ability to make GLP-1 can naturally decline as we get older and be impacted at even a young age by our environment full of processed food and exposure to chemicals—leaving us feeling hungrier than we were designed to feel. Dr. Stephanie, as a Doctor of Pharmacy, board certified in advanced diabetes management, and founder of Dr. Stephanie’s supplements, is excited to share her new product: GLP-Wonder. Unlike a medication that gives your body high amounts of synthetic GLP-1 hormone, this is a natural formula that is clinically proven to help your body make more of its own GLP-1. Take one simple little capsule every day to reduce cravings, suppress your appetite, and feel fuller and more satisfied when you eat, so you find yourself eating less and find it easier to make healthier food choices. GLP-1 is key in optimizing metabolic health, weight, blood sugar, heart health, brain health, and more. GLP-Wonder is a natural and gentle approach to boost GLP-1 without side effects. The whole foundation of Dr. Stephanie’s company is making natural supplement options that not only use science-backed ingredients but clinically studied doses—meaning you are getting high enough amounts of these natural ingredients to give you results—because it is the dose that makes the difference. All her products are clean, sourced from the highest quality, every batch is third-party tested for safety, and made in the USA. Like GLP-Wonder, Dr. Stephanie’s products are all about targeting hormone health. We talked about GLP-1 gut hormone, but she also offers products for insulin health—the main hormone in maintaining blood sugar balance. Natural ingredients can have very powerful and meaningful blood sugar benefits. Her Blood Sugar 24 Hour uses a custom blend of six vitamins and herbs to optimize insulin function to support healthy blood sugar levels around the clock. Pair this with her Carb & Sugar Blocker, which has premium grade Berberine, to help block carbohydrate absorption from food but also to fight insulin spikes —as insulin is a fat-storing hormone. Learn more or purchase GLP-Wonder and Blood Sugar support products at DrStephanies.com. GLP-Wonder is in stores at Walmart, and all her products are available nationwide in CVS and Walgreens—you can find them near the pharmacy.

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Are you looking for the best exercises to burn belly fat and tone your abs at home? This workout routine consists of exercises that will help you get a toned stomach and lose belly fat quickly. ⏱️ A good diet can help you get more out of your workouts. ⏱️ Don't go too hard on the first exercise, use it to warm up a tight body. ⏱️ If you have a hard time completing exercise, try increasing the rest between movements by 5 to 10 seconds. ⏱️ Try 2 to 3 sets in a row depending on your proficiency. ☆Sponsor this channel☆ https://www.youtube.com/channel/UCsCrgTwPv3kBrPF9omhQpzA/join #workout #fitness #homeworkout #hometraining 00:00 Mountain Climber 00:50 Knee Air Drive 01:38 Standing Side High Crunch 02:26 Twist March 03:14 Twisting Knee Up 04:02 Mountain Climber Cross 04:50 Fast Sit Up Slow Down 05:38 Lying Crunch 06:26 Alternate Leg Raise with Head up 07:14 Flutter Kicks IMPORTANT DISCLAIMER : Please understand that the title of the video may contain some intuitive and stimulating elements to increase the possibility of searching for content. Videos are produced by referring to fully verified exercise programs. Everyone is different, and there are no health or fitness solutions. For example, the push-ups, crunches, lunges, squats, sit-ups, leg-rises, etc. that are included in the video are very informative exercises that have traditionally been performed, but some people are injured by these movements. Our team is not a medical professional, and your health and safety are the most important. When copying our videos, please be careful to exercise in a safe environment, and we highly recommend that you seek advice from health and fitness professionals on exercise form and diet.

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READYYY für ein kurzes, intensives 10 MIN Fat Burning Beginner Workout?! ♥️ Dieses Workout ist Teil meiner kostenlosen 21 TAGE GET STARTED CHALLENGE: https://tina-halder.com/get-started-challenge/ Das kostenlose Home Workout Programm für Anfänger. ▸▸ Hol' dir hier deinen Trainingsplan kostenlos direkt auf dein Handy: https://tina-halder.com/trainingsplan/ Bei der Wahl der Übungen hab’ ich eine neue Routine zusammen gestellt, für jeden machbar ist – egal welches Fitnesslevel. Kein Springen, keine Jumping Jacks und keine Burpees - versprochen! Eines ist auf jeden Fall sicher – dieses Workout verbrennt eine Menge Kalorien aber wird dich überfordern!! Auch wenn’s erstmal hart klingt – es wird dir Spaß machen und ich bin mir sicher, dass du mindestens genauso viel Spaß haben wirst wie ich. Die Musik ist genial und die Side-Notiz, dass das Workout „nur“ 10 Minuten dauert macht es auf jeden Fall erträglich. Normalerweise versuche ich mich in den Workouts mit der Erklärung und Anleitung kurz zu halten. Diesmal musste ich immer wieder mal meinen „Senf“ dazu geben, damit du trotzdem durchhältst (oder musste ich mich sogar selbst motivieren :P ) …. eeegal! Meine Lieben, dieses Anfänger Workout macht Spaß! Probiert es einfach aus 😊 Wir brauchen keine Geräte, kein Equipment, noch nicht mal eine Sportmatte – jegliche Ausreden haben wir somit aus dem Weg geräumt. Was wir jedoch brauchen ist ein Sportoutfit, indem wir uns wohl fühlen. Jede Übung powern wir 40 Sekunden lang durch. Zwischen den Übungen erwartet dich eine 20-sekündige Pause, um dich von der Belastung zu erholen. Stell dir auch gerne etwas zu trinken bereit. Falls du mehr Pausen brauchst - NIMM SIE DIR ♥️ Hör auf deinen Körper und arbeite mit ihm - & niemals gegen ihn. Das solltest du noch wissen: Es liegt mir sehr am Herzen, dass sich niemand, absolut niemand, durch meine Workouts schlechter fühlt. Meine Home Workouts sollen dich herausfordern aber nicht überfordern. Du sollst dich besser und wohler in deinem Körper fühlen und gemeinsam mit ihm an deinem Ziel arbeiten - niemals gegen ihn. Wenn du mehr Pausen brauchst, nimm sie dir - es ist okay! Mein Online Shop: https://tina-halder.shop/ Weitere kostenlose Home Workout Trainingspläne: 28 Tage Get in Shape Challenge https://tina-halder.com/get-in-shape-challenge/ 21 Tage Sanduhr Figur Challenge https://tina-halder.com/workout/sanduhr-figur-challenge/ 14 Tage Flacher Bauch Challenge https://tina-halder.com/workout/flacher-bauch-challenge/ 21 Tage Get Fit Challenge https://tina-halder.com/get-fit-challenge/ Das erwartet dich in diesem Fat Burning Beginner Workout: Intro: 00:00 - 0:52 1. Hand to Knee Marches: 00:53 – 01:52 2. Raise Up: 01:53 – 02:52 3. Rotation Squat Punches: 02:53 – 03:52 4. Punch & Crunch, left: 03:53 – 04:52 5. Punch & Crunch, right: 04:53 – 05:52 6. Side Step no Jumping Jacks: 05:53 – 06:52 7. Full Speed Punches: 06:53 – 07:52 8. Slow Skater: 07:53 – 08:52 9. Hand to Feet Touches: 08:53 – 09:52 10. Side to Side Squats: 09:53 – 10:32 Outro: 10:33 - 10:56 ___ Meine Mission ist es, Menschen für eine gesunde Lebensweise zu begeistern - fernab von Diäten, Verboten und Zwängen. ___ #tinafitnessteam #herzensangelegenheit #getstartedchallenge 📩 Kontakt: [email protected] ▸ NEU: Mein Podcast "Body in Balance" ist da! Jetzt reinhören: https://open.spotify.com/show/5QkD98Mwx4XEFPYR4E6mve?si=064a8e7aad174a1b ▸ Hol' dir hier kostenloses Wissen rund um die Themen Abnehmen, Gesundheit und Ernährung: https://tina-halder.com/ ▸ Meine Ernährungsmethoden: https://tina-halder.com/ernaehrungsmethoden ▸ Mein Online Shop: https://tina-halder.shop/ ▸ Mein Backbuch "Eat Better - Enjoy More": https://tina-halder.com/kochbuch-winteredition/ ▸ Folge mir auf Instagram: https://www.instagram.com/tina.halder.official/ WICHTIGER Haftungsausschluss: Bitte beachte, dass alle meine Videos gemäß den SEO-Best Practices für die Auffindbarkeit von Inhalten betitelt sind. Leider kann dies bedeuten, dass Videotitel subjektiv sind und nicht als absolute Wahrheit angesehen werden sollten. Zum Beispiel ist die gezielte Fettverringerung nicht wissenschaftlich belegt, aber ein Videotitel könnte etwas anderes vorschlagen. Wenn du dich mir diesem Trainingsvideo anschließt, musst du einige Vorsichtsmaßnahmen treffen, da deine Gesundheit und Sicherheit am wichtigsten ist. Um Verletzungen oder Schäden zu vermeiden, musst du deine Gesundheit vor dem Training mit einem Arzt besprechen. Wenn du Fitnessübungen wie in diesem Video ohne Aufsicht durchführst, führst du sie auf dein eigenes Risiko durch. Wende dich an einen Fitnessprofi, um Ratschläge zur richtigen Ausführung und deine Trainingsform zu erhalten. Christina Halder ist nicht verantwortlich oder haftbar für Verletzungen oder Schäden, die du durch dieses Video erleidest.

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